| Literature DB >> 11418518 |
J S Friedberg1, C Skema, E D Baum, J Burdick, S A Vinogradov, D F Wilson, A D Horan, I Nachamkin.
Abstract
Photodynamic therapy is a technique for killing cells with visible light after pretreatment with a photosensitizing agent. We demonstrated significant in vitro fungicidal activity against Aspergillus fumigatus of the photosensitizer Green 2W, activated with 630 nm light. This effect was both inoculum- and light dose-dependent. At a Green 2W concentration of 31.5 mg/L, there was complete killing of 2.7 x 10(1) cfu/mL with a light dose of 110 J/cm(2) and up to 2.7 x 10(6) cfu/mL with a light dose of 385 J/cm(2).Entities:
Mesh：
Year: 2001 PMID： 11418518 DOI： 10.1093/jac/48.1.105
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790