Literature DB >> 11417034

Impact of prepackaging antimalarial drugs on cost to patients and compliance with treatment.

K Yeboah-Antwi1, J O Gyapong, I K Asare, G Barnish, D B Evans, S Adjei.   

Abstract

OBJECTIVE: To examine the extent to which district health teams could reduce the burden of malaria, a continuing major cause of mortality and morbidity, in a situation where severe resource constraints existed and integrated care was provided.
METHODS: Antimalarial drugs were prepackaged into unit doses in an attempt to improve compliance with full courses of chemotherapy.
FINDINGS: Compliance improved by approximately 20% in both adults and children. There were 50% reductions in cost to patients, waiting time at dispensaries and drug wastage at facilities. The intervention, which tended to improve both case and drug management at facilities, was well accepted by health staff and did not involve them in additional working time.
CONCLUSION: The prepackaging of antimalarials at the district level offers the prospect of improved compliance and a reduction in the spread of resistance.

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Year:  2001        PMID: 11417034      PMCID: PMC2566421     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  28 in total

Review 1.  Therapy of falciparum malaria in sub-saharan Africa: from molecule to policy.

Authors:  Peter Winstanley; Stephen Ward; Robert Snow; Alasdair Breckenridge
Journal:  Clin Microbiol Rev       Date:  2004-07       Impact factor: 26.132

Review 2.  Intervention to promote patients' adherence to antimalarial medication: a systematic review.

Authors:  Anjana Fuangchan; Teerapon Dhippayom; Chuenjid Kongkaew
Journal:  Am J Trop Med Hyg       Date:  2013-10-28       Impact factor: 2.345

Review 3.  Unit-dose packaged drugs for treating malaria.

Authors:  L Orton; G Barnish
Journal:  Cochrane Database Syst Rev       Date:  2005-04-18

Review 4.  Interventions for enhancing medication adherence.

Authors:  Robby Nieuwlaat; Nancy Wilczynski; Tamara Navarro; Nicholas Hobson; Rebecca Jeffery; Arun Keepanasseril; Thomas Agoritsas; Niraj Mistry; Alfonso Iorio; Susan Jack; Bhairavi Sivaramalingam; Emma Iserman; Reem A Mustafa; Dawn Jedraszewski; Chris Cotoi; R Brian Haynes
Journal:  Cochrane Database Syst Rev       Date:  2014-11-20

5.  Parents' perceptions, attitudes and acceptability of treatment of childhood malaria with artemisinin combination therapies in ghana.

Authors:  G O Adjei; A K Darkwah; B Q Goka; C Bart-Plange; M L Alifrangis; J A L Kurtzhals; O P Rodrigues
Journal:  Ghana Med J       Date:  2009-09

6.  Compliance with a three-day course of artesunate-mefloquine combination and baseline anti-malarial treatment in an area of Thailand with highly multidrug resistant falciparum malaria.

Authors:  Kanungnit Congpuong; Pongwit Bualombai; Vick Banmairuroi; Kesara Na-Bangchang
Journal:  Malar J       Date:  2010-02-04       Impact factor: 2.979

7.  Adherence to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana: A Randomised Trial of Supervised versus Unsupervised Drug Administration.

Authors:  Kwaku Poku Asante; Ruth Owusu; David Dosoo; Elizabeth Awini; George Adjei; Seeba Amenga Etego; Daniel Chandramohan; Seth Owusu-Agyei
Journal:  J Trop Med       Date:  2009-10-21

8.  Improvements in access to malaria treatment in Tanzania following community, retail sector and health facility interventions -- a user perspective.

Authors:  Sandra Alba; Angel Dillip; Manuel W Hetzel; Iddy Mayumana; Christopher Mshana; Ahmed Makemba; Mathew Alexander; Brigit Obrist; Alexander Schulze; Flora Kessy; Hassan Mshinda; Christian Lengeler
Journal:  Malar J       Date:  2010-06-15       Impact factor: 2.979

9.  Mobile phone text messaging: tool for malaria control in Africa.

Authors:  Dejan Zurovac; Ambrose O Talisuna; Robert W Snow
Journal:  PLoS Med       Date:  2012-02-21       Impact factor: 11.069

10.  Factors related to compliance to anti-malarial drug combination: example of amodiaquine/sulphadoxine-pyrimethamine among children in rural Senegal.

Authors:  Aurélia Souares; Richard Lalou; Ibra Sene; Diarietou Sow; Jean-Yves Le Hesran
Journal:  Malar J       Date:  2009-06-04       Impact factor: 2.979

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