Literature DB >> 11406411

RNA editing by base deamination: more enzymes, more targets, new mysteries.

A P Gerber1, W Keller.   

Abstract

The posttranscriptional modification of messenger RNA precursors (pre-mRNAs) by base deamination can profoundly alter the physiological function of the encoded proteins. The recent identification of tRNA-specific adenosine deaminases (ADATs) has led to the suggestion that these enzymes, as well as the cytidine and adenosine deaminases acting on pre-mRNAs (CDARs and ADARs), belong to a superfamily of RNA-dependent deaminases. This superfamily might have evolved from an ancient cytidine deaminase. This article reviews the reactions catalysed by these enzymes and discusses their evolutionary relationships.

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Year:  2001        PMID： 11406411     DOI： 10.1016/s0968-0004(01)01827-8

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  87 in total

Review 1.  RNA editing by adenosine deaminases that act on RNA.

Authors:  Brenda L Bass
Journal:  Annu Rev Biochem       Date:  2001-11-09       Impact factor: 23.643

2.  Coordination of editing and splicing of glutamate receptor pre-mRNA.

Authors:  Eva Bratt; Marie Ohman
Journal:  RNA       Date:  2003-03       Impact factor: 4.942

3.  Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain.

Authors:  Alexander Strehblow; Martina Hallegger; Michael F Jantsch
Journal:  Mol Biol Cell       Date:  2002-11       Impact factor: 4.138

4.  Characterization of RNA determinants recognized by the arginine- and proline-rich region of Us11, a herpes simplex virus type 1-encoded double-stranded RNA binding protein that prevents PKR activation.

Authors:  David Khoo; Cesar Perez; Ian Mohr
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

5.  tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features.

Authors:  Christian Marck; Henri Grosjean
Journal:  RNA       Date:  2002-10       Impact factor: 4.942

Review 6.  Activity regulation of adenosine deaminases acting on RNA (ADARs).

Authors:  Cesare Orlandi; Alessandro Barbon; Sergio Barlati
Journal:  Mol Neurobiol       Date:  2011-11-20       Impact factor: 5.590

Review 7.  The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.

Authors:  Christopher S Nabel; Sara A Manning; Rahul M Kohli
Journal:  ACS Chem Biol       Date:  2011-10-31       Impact factor: 5.100

Review 8.  Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases.

Authors:  Elisa Orecchini; Loredana Frassinelli; Silvia Galardi; Silvia Anna Ciafrè; Alessandro Michienzi
Journal:  Chromosome Res       Date:  2018-02-02       Impact factor: 5.239

9.  Analysis of human mRNAs with the reference genome sequence reveals potential errors, polymorphisms, and RNA editing.

Authors:  Terrence S Furey; Mark Diekhans; Yontao Lu; Tina A Graves; Lachlan Oddy; Jennifer Randall-Maher; LaDeana W Hillier; Richard K Wilson; David Haussler
Journal:  Genome Res       Date:  2004-10       Impact factor: 9.043

10.  Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome.

Authors:  Jiqiang Ling; Hervé Roy; Daoming Qin; Mary Anne T Rubio; Juan D Alfonzo; Kurt Fredrick; Michael Ibba
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-18       Impact factor: 11.205
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