Literature DB >> 11406387

Determination of protein function, evolution and interactions by structural genomics.

S A Teichmann1, A G Murzin, C Chothia.   

Abstract

The genome sequencing projects and knowledge of the entire protein repertoires of many organisms have prompted new procedures and techniques for the large-scale determination of protein structure, function and interactions. Recently, new work has been carried out on the determination of the function and evolutionary relationships of proteins by experimental structural genomics, and the discovery of protein-protein interactions by computational structural genomics.

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Year:  2001        PMID: 11406387     DOI: 10.1016/s0959-440x(00)00215-3

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN: 0959-440X            Impact factor:   6.809


  38 in total

1.  Relating whole-genome expression data with protein-protein interactions.

Authors:  Ronald Jansen; Dov Greenbaum; Mark Gerstein
Journal:  Genome Res       Date:  2002-01       Impact factor: 9.043

2.  MAMMOTH (matching molecular models obtained from theory): an automated method for model comparison.

Authors:  Angel R Ortiz; Charlie E M Strauss; Osvaldo Olmea
Journal:  Protein Sci       Date:  2002-11       Impact factor: 6.725

3.  Future directions in protein function prediction.

Authors:  Ihsan A Shehadi; Huyuan Yang; Mary Jo Ondrechen
Journal:  Mol Biol Rep       Date:  2002-12       Impact factor: 2.316

4.  Annotation in three dimensions. PINTS: Patterns in Non-homologous Tertiary Structures.

Authors:  Alexander Stark; Robert B Russell
Journal:  Nucleic Acids Res       Date:  2003-07-01       Impact factor: 16.971

5.  SVM-Prot: Web-based support vector machine software for functional classification of a protein from its primary sequence.

Authors:  C Z Cai; L Y Han; Z L Ji; X Chen; Y Z Chen
Journal:  Nucleic Acids Res       Date:  2003-07-01       Impact factor: 16.971

6.  Identification of protein biochemical functions by similarity search using the molecular surface database eF-site.

Authors:  Kengo Kinoshita; Haruki Nakamura
Journal:  Protein Sci       Date:  2003-08       Impact factor: 6.725

Review 7.  Structural genomics: computational methods for structure analysis.

Authors:  Sharon Goldsmith-Fischman; Barry Honig
Journal:  Protein Sci       Date:  2003-09       Impact factor: 6.725

8.  Prediction of functional sites by analysis of sequence and structure conservation.

Authors:  Anna R Panchenko; Fyodor Kondrashov; Stephen Bryant
Journal:  Protein Sci       Date:  2004-03-09       Impact factor: 6.725

9.  Identification of interface residues in protease-inhibitor and antigen-antibody complexes: a support vector machine approach.

Authors:  Changhui Yan; Vasant Honavar; Drena Dobbs
Journal:  Neural Comput Appl       Date:  2004-06-01       Impact factor: 5.606

10.  Structure-based functional identification of a novel heme-binding protein from Thermus thermophilus HB8.

Authors:  Akio Ebihara; Akihiro Okamoto; Yukihide Kousumi; Hitoshi Yamamoto; Ryoji Masui; Norikazu Ueyama; Shigeyuki Yokoyama; Seiki Kuramitsu
Journal:  J Struct Funct Genomics       Date:  2005
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