Literature DB >> 11405721

Progress toward the total synthesis of kalihinane diterpenoids.

R D White1, J L Wood.   

Abstract

[see structure]. Studies toward the total synthesis of marine diterpenoids isolated from Acanthella sp., e.g., kalihinol A, are described. Efficient construction of the functionalized trans-decalin core (11) is achieved through intramolecular Diels-Alder cyclization followed by diastereoselective epoxidation and aziridination.

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Year:  2001        PMID: 11405721     DOI: 10.1021/ol015828k

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  9 in total

1.  Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives.

Authors:  Norikazu Sakakibara; Gianfranco Balboni; Cenzo Congiu; Valentina Onnis; Yosuke Demizu; Takashi Misawa; Masaaki Kurihara; Yoshihisa Kato; Tokumi Maruyama; Masaaki Toyama; Mika Okamoto; Masanori Baba
Journal:  Antivir Chem Chemother       Date:  2015-10-28

2.  Total Synthesis of (±)-Dragmacidin E: Problems Solved and Lessons Learned.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Synlett       Date:  2012-08       Impact factor: 2.454

3.  Design, synthesis, and anti-HIV-1 activity of 1-aromatic methyl-substituted 3-(3,5-dimethylbenzyl)uracil and N-3,5-dimethylbenzyl-substituted urea derivatives.

Authors:  Norikazu Sakakibara; Masanori Baba; Mika Okamoto; Masaaki Toyama; Yosuke Demizu; Takashi Misawa; Masaaki Kurihara; Kohji Irie; Yoshihisa Kato; Tokumi Maruyama
Journal:  Antivir Chem Chemother       Date:  2015-02

4.  Dragmacidin E synthesis studies. Preparation of a model heptacyclic core structure.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Org Lett       Date:  2010-10-15       Impact factor: 6.005

5.  Stereocontrolled Synthesis of Kalihinol C.

Authors:  Christopher A Reiher; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2017-03-02       Impact factor: 15.419

Review 6.  Syntheses and biological studies of marine terpenoids derived from inorganic cyanide.

Authors:  Martin J Schnermann; Ryan A Shenvi
Journal:  Nat Prod Rep       Date:  2015-04       Impact factor: 13.423

7.  Cyclic Metalated Nitriles: Stereoselective Cyclizations to cis- and trans-Hydrindanes, Decalins, and Bicyclo[4.3.0]undecanes.

Authors:  Fraser F Fleming; Subramanyham Gudipati
Journal:  European J Org Chem       Date:  2008-11-01

8.  Synthesis and potent antimalarial activity of kalihinol B.

Authors:  Mary Elisabeth Daub; Jacques Prudhomme; Karine Le Roch; Christopher D Vanderwal
Journal:  J Am Chem Soc       Date:  2015-04-09       Impact factor: 15.419

9.  Antimalarial Properties of Simplified Kalihinol Analogues.

Authors:  Mary Elisabeth Daub; Jacques Prudhomme; Choukri Ben Mamoun; Karine G Le Roch; Christopher D Vanderwal
Journal:  ACS Med Chem Lett       Date:  2017-02-16       Impact factor: 4.345

  9 in total

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