Literature DB >> 1140386

[Dialkylaminoalkylbenzimidazoles of pharmacological importance. IV].

G Paglietti, V Boido, F Sparatore.   

Abstract

In order to improve the analgesic and antiarrhythmic activities of 1-dialkylaminoalkyl-2-benzotriazolylmethylbenzimidazoles previously described, forty derivatives with a chlorine, trifluoromethyl, acetyl or nitrogroup in 5 position were prepared.

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Year:  1975        PMID： 1140386

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN： 0430-0920


  4 in total

1.  Primary anti-proliferative activity evaluation of 1-(quinolizidin-1'-yl)methyl- and 1-(ω-tert-amino)alkyl-substituted 2-phenyl-, 2-benzyl- and 2-[(benzotriazol-1/2-yl)methyl]benzimidazoles on human cancer cell lines.

Authors:  Michele Tonelli; Bruno Tasso; Lorenzo Mina; Giuseppe Paglietti; Vito Boido; Fabio Sparatore
Journal:  Mol Divers       Date:  2013-04-13       Impact factor: 2.943

2.  Orally active fusion inhibitor of respiratory syncytial virus.

Authors:  Christopher Cianci; Kuo-Long Yu; Keith Combrink; Ny Sin; Bradley Pearce; Alan Wang; Rita Civiello; Stacey Voss; Guangxiang Luo; Kathy Kadow; Eugene V Genovesi; Brian Venables; Hatice Gulgeze; Ashok Trehan; Jennifer James; Lucinda Lamb; Ivette Medina; Julia Roach; Zheng Yang; Lisa Zadjura; Richard Colonno; Junius Clark; Nicholas Meanwell; Mark Krystal
Journal:  Antimicrob Agents Chemother       Date:  2004-02       Impact factor: 5.191

3.  Exploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET prediction.

Authors:  Michele Tonelli; Elena Cichero; Alì Mokhtar Mahmoud; Alessandro Rabbito; Bruno Tasso; Paola Fossa; Alessia Ligresti
Journal:  Medchemcomm       Date:  2018-10-10       Impact factor: 3.597

4.  1-[2-(1H-Benzimidazol-2-yl)eth-yl]-1H-1,2,3-benzotriazole.

Authors:  Zhong Zhang; Wei Lu; Difeng Wu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-11-05
  4 in total

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