Literature DB >> 11402013

Expression of genes encoding Th1 cell-activating cytokines and lymphoid homing chemokines by chlamydia-pulsed dendritic cells correlates with protective immunizing efficacy.

J H Shaw1, V R Grund, L Durling, H D Caldwell.   

Abstract

We studied the expression of cytokines, chemokines, and chemokine receptors by the RNase protection assay in chlamydia-pulsed dendritic cells to better understand their potent anti-chlamydial immunizing properties. We found that chlamydia-pulsed dendritic cells express a complex profile of inflammatory and immunomodulatory molecules. These include CCR-7, interleukin-12, and interferon-induced protein 10, molecules that might influence the homing of pulsed dendritic cells to the site of chlamydial infection and the induction of a local protective CD4(+) Th1 cellular immunity.

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Year:  2001        PMID： 11402013      PMCID： PMC98546          DOI： 10.1128/IAI.69.7.4667-4672.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

Review 1.  The role of chemokines in the regulation of dendritic cell trafficking.

Authors:  S Sozzani; P Allavena; A Vecchi; A Mantovani
Journal:  J Leukoc Biol       Date:  1999-07       Impact factor: 4.962

Review 2.  Chemokines: a new classification system and their role in immunity.

Authors:  A Zlotnik; O Yoshie
Journal:  Immunity       Date:  2000-02       Impact factor: 31.745

Review 3.  Immunobiology of dendritic cells.

Authors:  J Banchereau; F Briere; C Caux; J Davoust; S Lebecque; Y J Liu; B Pulendran; K Palucka
Journal:  Annu Rev Immunol       Date:  2000       Impact factor: 28.527

4.  IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection.

Authors:  I A Khan; J A MacLean; F S Lee; L Casciotti; E DeHaan; J D Schwartzman; A D Luster
Journal:  Immunity       Date:  2000-05       Impact factor: 31.745

Review 5.  Dendritic cells in the T-cell areas of lymphoid organs.

Authors:  R M Steinman; M Pack; K Inaba
Journal:  Immunol Rev       Date:  1997-04       Impact factor: 12.988

Review 6.  Chlamydial lipopolysaccharide.

Authors:  P Kosma
Journal:  Biochim Biophys Acta       Date:  1999-10-08

7.  Vaccination of mice with DNA plasmids coding for the Chlamydia trachomatis major outer membrane protein elicits an immune response but fails to protect against a genital challenge.

Authors:  S Pal; K M Barnhart; Q Wei; A M Abai; E M Peterson; L M de la Maza
Journal:  Vaccine       Date:  1999-02-05       Impact factor: 3.641

8.  Suppression of endogenous IL-10 gene expression in dendritic cells enhances antigen presentation for specific Th1 induction: potential for cellular vaccine development.

Authors:  J U Igietseme; G A Ananaba; J Bolier; S Bowers; T Moore; T Belay; F O Eko; D Lyn; C M Black
Journal:  J Immunol       Date:  2000-04-15       Impact factor: 5.422

9.  DNA vaccination with the major outer-membrane protein gene induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection.

Authors:  D Zhang; X Yang; J Berry; C Shen; G McClarty; R C Brunham
Journal:  J Infect Dis       Date:  1997-10       Impact factor: 5.226

10.  Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydiae.

Authors:  H Su; R Messer; W Whitmire; E Fischer; J C Portis; H D Caldwell
Journal:  J Exp Med       Date:  1998-09-07       Impact factor: 14.307
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  18 in total

1.  Protective immunity against mouse upper genital tract pathology correlates with high IFNγ but low IL-17 T cell and anti-secretion protein antibody responses induced by replicating chlamydial organisms in the airway.

Authors:  Chunxue Lu; Hao Zeng; Zhihong Li; Lei Lei; I-Tien Yeh; Yimou Wu; Guangming Zhong
Journal:  Vaccine       Date:  2011-11-10       Impact factor: 3.641

2.  Chlamydia-specific CD4 T cell clones control Chlamydia muridarum replication in epithelial cells by nitric oxide-dependent and -independent mechanisms.

Authors:  Krupakar Jayarapu; Micah Kerr; Susan Ofner; Raymond M Johnson
Journal:  J Immunol       Date:  2010-10-29       Impact factor: 5.422

3.  Type 1 T-cell responses in chlamydial lung infections are associated with local MIP-1alpha response.

Authors:  Naihong Zhang; Zhaoe Wang; Xiaofei Tang; Haiping Wang; Hongzhao Li; Huanjun Huang; Hong Bai; Xi Yang
Journal:  Cell Mol Immunol       Date:  2010-07-12       Impact factor: 11.530

4.  Chemokine and chemokine receptor dynamics during genital chlamydial infection.

Authors:  Tesfaye Belay; Francis O Eko; Godwin A Ananaba; Samera Bowers; Terri Moore; Deborah Lyn; Joseph U Igietseme
Journal:  Infect Immun       Date:  2002-02       Impact factor: 3.441

5.  A live and inactivated Chlamydia trachomatis mouse pneumonitis strain induces the maturation of dendritic cells that are phenotypically and immunologically distinct.

Authors:  Jose Rey-Ladino; Kasra M Koochesfahani; Michelle L Zaharik; Caixia Shen; Robert C Brunham
Journal:  Infect Immun       Date:  2005-03       Impact factor: 3.441

6.  Chlamydia muridarum-specific CD4 T-cell clones recognize infected reproductive tract epithelial cells in an interferon-dependent fashion.

Authors:  Krupakar Jayarapu; Micah S Kerr; Adrian Katschke; Raymond M Johnson
Journal:  Infect Immun       Date:  2009-08-10       Impact factor: 3.441

7.  Genetic profiling of dendritic cells exposed to live- or ultraviolet-irradiated Chlamydia muridarum reveals marked differences in CXC chemokine profiles.

Authors:  Michelle L Zaharik; Tarun Nayar; Rick White; Caixia Ma; Bruce A Vallance; Nadine Straka; Xiaozhou Jiang; Jose Rey-Ladino; Caixia Shen; Robert C Brunham
Journal:  Immunology       Date:  2006-10-31       Impact factor: 7.397

8.  A Chlamydia-Specific TCR-Transgenic Mouse Demonstrates Th1 Polyfunctionality with Enhanced Effector Function.

Authors:  Taylor B Poston; Yanyan Qu; Jenna Girardi; Catherine M O'Connell; Lauren C Frazer; Ali N Russell; McKensie Wall; Uma M Nagarajan; Toni Darville
Journal:  J Immunol       Date:  2017-08-30       Impact factor: 5.422

9.  Effective induction of acquired resistance to Listeria monocytogenes by immunizing mice with in vivo-infected dendritic cells.

Authors:  Hiroshi Sashinami; Akio Nakane; Yoichiro Iwakura; Mutsuo Sasaki
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

10.  Prostaglandin E2 modulates dendritic cell function during chlamydial genital infection.

Authors:  Wei Liu; Kathleen Ann Kelly
Journal:  Immunology       Date:  2007-08-03       Impact factor: 7.397
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