Mechanical thrombectomy as a first-line treatment for arterial occlusion.

The use of percutaneous mechanical thrombectomy devices to restore flow to an acutely ischemic limb is gaining popularity. Potential benefits include the minimally invasive nature of the procedure, rapid blood flow restoration, and a decrease in the dose and duration of adjunctive pharmacologic thrombolytic agents when required. A detailed description of the currently available mechanical thrombectomy devices, preclinical device evaluation, and published clinical trials for the management of acute limb-threatening ischemia are provided. Copyright 2001 by W.B. Saunders Company