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Literature DB >> 11397077

Does a stretched DNA structure dictate the helical geometry of RecA-like filaments?

Abstract

Proteins in the RecA/Rad51/RadA/UvsX family form helical filaments on DNA in which the DNA is stretched and untwisted. A comparison of the average helical parameters of these filaments from five different proteins, obtained from archaea, eubacteria and eukaryotes, suggests that an intrinsic state of DNA may be responsible for the conservation of these particular filament forms across evolution. In this view, these proteins stabilize this existing state of DNA, rather than induce a novel conformation. Copyright 2001 Academic Press.

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Year: 2001 PMID： 11397077 DOI： 10.1006/jmbi.2001.4686

Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469

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Cited

10 in total

1. Mechanism of RecA-mediated homologous recombination revisited by single molecule nanomanipulation.

Authors: Renaud Fulconis; Judith Mine; Aurélien Bancaud; Marie Dutreix; Jean-Louis Viovy
Journal: EMBO J Date: 2006-08-31 Impact factor: 11.598

2. The structure of DNA overstretched from the 5'5' ends differs from the structure of DNA overstretched from the 3'3' ends.

Authors: Claudia Danilowicz; Charles Limouse; Kristi Hatch; Alyson Conover; Vincent W Coljee; Nancy Kleckner; Mara Prentiss
Journal: Proc Natl Acad Sci U S A Date: 2009-07-28 Impact factor: 11.205

3. Strand invasion promoted by recombination protein beta of coliphage lambda.

Authors: Nataliya Rybalchenko; Efim I Golub; Baoyuan Bi; Charles M Radding
Journal: Proc Natl Acad Sci U S A Date: 2004-12-01 Impact factor: 11.205

4. Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.

Authors: Jingfei Xu; Lingyun Zhao; Yuanyuan Xu; Weixing Zhao; Patrick Sung; Hong-Wei Wang
Journal: Nat Struct Mol Biol Date: 2016-12-12 Impact factor: 15.369

5. pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae.

Authors: D E C S Rao; Yu Luo
Journal: Protein Pept Lett Date: 2014-07 Impact factor: 1.890

Does a stretched DNA structure dictate the helical geometry of RecA-like filaments?

1. Mechanism of RecA-mediated homologous recombination revisited by single molecule nanomanipulation.

2. The structure of DNA overstretched from the 5'5' ends differs from the structure of DNA overstretched from the 3'3' ends.

3. Strand invasion promoted by recombination protein beta of coliphage lambda.

4. Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.

5. pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae.

6. An integrative approach to the study of filamentous oligomeric assemblies, with application to RecA.

7. Structure of the hDmc1-ssDNA filament reveals the principles of its architecture.

8. Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filaments.

9. Structural and torsional properties of the RAD51-dsDNA nucleoprotein filament.

10. Weaving DNA strands: structural insight on ATP hydrolysis in RecA-induced homologous recombination.