| Literature DB >> 11392537 |
R Tedesco1, M K Youngman, S R Wilson, J A Katzenellenbogen.
Abstract
To prepare novel estrogen receptor (ER) ligands, we have developed a facile approach to substituted hexahydrochrysene and tetrahydrobenzo[a]fluorene systems. Substituents, including basic side chains, were added to these systems, and their binding affinity to ERalpha and ERbeta, and in some cases their transcriptional activity were evaluated.Entities:
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Year: 2001 PMID： 11392537 DOI： 10.1016/s0960-894x(01)00189-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823