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Literature DB >> 11388673

Frequency of celiac disease in individuals with Down syndrome in the United States.

J Mackey¹, W R Treem, G Worley, A Boney, P Hart, P S Kishnani.

Abstract

Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.

Entities: Disease

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Year: 2001 PMID： 11388673 PMCID： PMC2706421 DOI： 10.1177/000992280104000502

Source DB: PubMed Journal: Clin Pediatr (Phila) ISSN： 0009-9228 Impact factor: 1.168

14 in total

Frequency of celiac disease in individuals with Down syndrome in the United States.

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6. Assessment of coeliac disease prevalence in patients with Down syndrome in Poland - a multi-centre study.

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