Literature DB >> 113840

Urinary 4-hydroxy-3-methoxyphenylglycol is not a predictor for clinical response to amitriptyline in depressive illness.

A Coppen, V A Rama Rao, C R Ruthven, B L Goodwin, M Sandler.   

Abstract

The urinary excretion of 4-hydroxy-3-methoxyphenylglycol was compared in a group of 23 depressive patients and 27 control subjects of similar age. There was no difference between patients and controls although female controls excreted less than males. After 6 weeks' treatment with 150 mg daily of amitriptyline there was no correlation between therapeutic response and pretreatment urinary excretion value.

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Year:  1979        PMID： 113840     DOI： 10.1007/bf00427352

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  19 in total

1.  CLINICAL TRIAL OF THE TREATMENT OF DEPRESSIVE ILLNESS. REPORT TO THE MEDICAL RESEARCH COUNCIL BY ITS CLINICAL PSYCHIATRY COMMITTEE.

Authors:  M THIERY
Journal:  Br Med J       Date:  1965-04-03

2.  A rating scale for depression.

Authors:  M HAMILTON
Journal:  J Neurol Neurosurg Psychiatry       Date:  1960-02       Impact factor: 10.154

3.  A rapid assay of 4-hydroxy-3-methoxyphenylglycol in urine.

Authors:  L Fellows; P Riederer; M Sandler
Journal:  Clin Chim Acta       Date:  1975-03-10       Impact factor: 3.786

4.  Metabolic pathways of dopamine and norepinephrine in rabbit brain in vitro.

Authors:  C O Rutledge; J Jonason
Journal:  J Pharmacol Exp Ther       Date:  1967-09       Impact factor: 4.030

5.  Determination of 3-methoxy-4-hydroxyphenylglycol in urine and the effect of diet on its excretion.

Authors:  N S Sharpless
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1977-10

Review 6.  The biochemistry of affective disorders.

Authors:  A Coppen
Journal:  Br J Psychiatry       Date:  1967-11       Impact factor: 9.319

7.  M.H.P.G. excretion and clinical classification in depressive disorders.

Authors:  J J Schildkraut; B A Keeler; E L Grab; J Kantrowich; E Hartmann
Journal:  Lancet       Date:  1973-06-02       Impact factor: 79.321

8.  In vivo studies of the metabolism of norepinephrine in the central nervous system.

Authors:  J W Maas; D H Landis
Journal:  J Pharmacol Exp Ther       Date:  1968-09       Impact factor: 4.030

9.  Brain histamine receptors as targets for antidepressant drugs.

Authors:  P D Kanof; P Greengard
Journal:  Nature       Date:  1978-03-23       Impact factor: 49.962

10.  Noradrenaline, depressive illness, and the action of amitriptyline.

Authors:  K Ghose; A Coppen
Journal:  Psychopharmacology (Berl)       Date:  1977-08-31       Impact factor: 4.530
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  6 in total

1.  MHPG excretion in endogenous depression: relationship to clinical state and the effects of ECT.

Authors:  M H Joseph; D Risby; T J Crow; J F Deakin; E C Johnstone; P Lawler
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

2.  Urinary 3-methoxy, 4-hydroxyphenylethylene glycol and therapeutic response to maprotiline and indalpine in major depression.

Authors:  H Loo; C Benkelfat; J M Vanelle; T Dennis; M F Poirier; J P Olie; B Scatton
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

3.  Toward a biochemical classification of depressive disorders. III: Pretreatment urinary MHPG levels as predictors of response to treatment with maprotiline.

Authors:  A F Schatzberg; A H Rosenbaum; P J Orsulak; W A Rohde; T Maruta; E R Kruger; J O Cole; J J Schildkraut
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

4.  Depressive-like behavior observed with a minimal loss of locus coeruleus (LC) neurons following administration of 6-hydroxydopamine is associated with electrophysiological changes and reversed with precursors of norepinephrine.

Authors:  Patricia Szot; Allyn Franklin; Cristina Miguelez; Yangqing Wang; Igor Vidaurrazaga; Luisa Ugedo; Carl Sikkema; Charles W Wilkinson; Murray A Raskind
Journal:  Neuropharmacology       Date:  2015-09-08       Impact factor: 5.250

5.  Do urinary MHPG and plasma drug levels correlate with response to amitriptyline therapy?

Authors:  H J Gaertner; F Kreuter; G Scharek; G Wiatr; U Breyer-Pfaff
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

Review 6.  Psychotherapeutic drugs and biogenic amines. Current concepts and therapeutic implications.

Authors:  W Z Potter
Journal:  Drugs       Date:  1984-08       Impact factor: 9.546
  6 in total

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