Literature DB >> 11377643

WHO systematic review of randomised controlled trials of routine antenatal care.

G Carroli1, J Villar, G Piaggio, D Khan-Neelofur, M Gülmezoglu, M Mugford, P Lumbiganon, U Farnot, P Bersgjø.   

Abstract

BACKGROUND: There is a lack of strong evidence on the effectiveness of the content, frequency, and timing of visits in standard antenatal-care programmes. We undertook a systematic review of randomised trials assessing the effectiveness of different models of antenatal care. The main hypothesis was that a model with a lower number of antenatal visits, with or without goal-oriented components, would be as effective as the standard antenatal-care model in terms of clinical outcomes, perceived satisfaction, and costs.
METHODS: The interventions compared were the provision of a lower number of antenatal visits (new model) and a standard antenatal-visits programme. The selected outcomes were pre-eclampsia, urinary-tract infection, postpartum anaemia, maternal mortality, low birthweight, and perinatal mortality. We also selected measures of women's satisfaction with care and cost-effectiveness. This review drew on the search strategy developed for the Cochrane Pregnancy and Childbirth Group of the Cochrane Collaboration.
FINDINGS: Seven eligible randomised controlled trials were identified. 57418 women participated in these studies: 30799 in the new-model groups (29870 with outcome data) and 26619 in the standard-model groups (25821 with outcome data). There was no clinically differential effect of the reduced number of antenatal visits when the results were pooled for pre-eclampsia (typical odds ratio 0.91 [95% CI 0.66-1.26]), urinary-tract infection (0.93 [0.79-1.10]). postpartum anaemia (1.01), maternal mortality (0.91 [0.55-1.51]), or low birthweight (1.04 [0.93-1.17]). The rates of perinatal mortality were similar, although the rarity of the outcome did not allow formal statistical equivalence to be attained. Some dissatisfaction with care, particularly among women in more developed countries, was observed with the new model. The cost of the new model was equal to or less than that of the standard model.
INTERPRETATION: A model with a reduced number of antenatal visits, with or without goal-oriented components, could be introduced into clinical practice without risk to mother or baby, but some degree of dissatisfaction by the mother could be expected. Lower costs can be achieved.

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Mesh:

Year:  2001        PMID: 11377643     DOI: 10.1016/S0140-6736(00)04723-1

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  136 in total

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Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

Review 2.  Alternative versus standard packages of antenatal care for low-risk pregnancy.

Authors:  Therese Dowswell; Guillermo Carroli; Lelia Duley; Simon Gates; A Metin Gülmezoglu; Dina Khan-Neelofur; Gilda Gp Piaggio
Journal:  Cochrane Database Syst Rev       Date:  2010-10-06

3.  Antenatal care and pregnancy outcomes in a safe motherhood health voucher system in rural Kenya, 2007-2013.

Authors:  A-B Kihara; A D Harries; K Bissell; W Kizito; R Van Den Berg; S Mueke; A Mwangi; J C Sitene; D Gathara; R J Kosgei; J Kiarie; P Gichangi
Journal:  Public Health Action       Date:  2015-03-21

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Review 8.  A review of the impact of antenatal care for Australian Indigenous women and attempts to strengthen these services.

Authors:  Alice R Rumbold; Joan Cunningham
Journal:  Matern Child Health J       Date:  2007-06-19

Review 9.  Delivery arrangements for health systems in low-income countries: an overview of systematic reviews.

Authors:  Agustín Ciapponi; Simon Lewin; Cristian A Herrera; Newton Opiyo; Tomas Pantoja; Elizabeth Paulsen; Gabriel Rada; Charles S Wiysonge; Gabriel Bastías; Lilian Dudley; Signe Flottorp; Marie-Pierre Gagnon; Sebastian Garcia Marti; Claire Glenton; Charles I Okwundu; Blanca Peñaloza; Fatima Suleman; Andrew D Oxman
Journal:  Cochrane Database Syst Rev       Date:  2017-09-13

10.  Prenatal care demand and its effects on birth outcomes by birth defect status in Argentina.

Authors:  George L Wehby; Jeffrey C Murray; Eduardo E Castilla; Jorge S Lopez-Camelo; Robert L Ohsfeldt
Journal:  Econ Hum Biol       Date:  2008-10-30       Impact factor: 2.184

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