Literature DB >> 1137602

On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.

R R Rando.   

Abstract

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Year:  1975        PMID： 1137602     DOI： 10.1016/0006-2952(75)90055-6

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  7 in total

1.  The exocellular DD-carboxypeptidase-endopeptidase of Streptomyces albus G. Interaction with beta-lactam antibiotics.

Authors:  J M Frère; F Geurts; J M Ghuysen
Journal:  Biochem J       Date:  1978-12-01       Impact factor: 3.857

2.  Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Authors:  Jonathan Lowther; Beverley A Yard; Kenneth A Johnson; Lester G Carter; Venugopal T Bhat; Marine C C Raman; David J Clarke; Britta Ramakers; Stephen A McMahon; James H Naismith; Dominic J Campopiano
Journal:  Mol Biosyst       Date:  2010-05-05

3.  Strategies for discovering and derisking covalent, irreversible enzyme inhibitors.

Authors:  Douglas S Johnson; Eranthie Weerapana; Benjamin F Cravatt
Journal:  Future Med Chem       Date:  2010-06       Impact factor: 3.808

4.  Asparagine synthetase in corn roots.

Authors:  I Stulen; A Oaks
Journal:  Plant Physiol       Date:  1977-11       Impact factor: 8.340

5.  Abnormal synthesis of cartilage-characteristic proteoglycan in azaserine-induced micromelial limbs.

Authors:  A Honda; I Tsuboi; K Kimata; Y Hirabayashi; K Yamada; Y Mori
Journal:  Biochem J       Date:  1989-07-15       Impact factor: 3.857

6.  Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis.

Authors:  Samiul Hasan; Sabine Daugelat; P S Srinivasa Rao; Mark Schreiber
Journal:  PLoS Comput Biol       Date:  2006-06-09       Impact factor: 4.475

7.  A Four-Point Screening Method for Assessing Molecular Mechanism of Action (MMOA) Identifies Tideglusib as a Time-Dependent Inhibitor of Trypanosoma brucei GSK3β.

Authors:  Zachary T Swinney; Brad A Haubrich; Shuangluo Xia; Chakk Ramesha; Stephen R Gomez; Paul Guyett; Kojo Mensa-Wilmot; David C Swinney
Journal:  PLoS Negl Trop Dis       Date:  2016-03-04
  7 in total

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