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Literature DB >> 1137391

Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum.

Abstract

The acetylating radioenzymatic assay of aminoglycosides was modified by using [(3)H]acetyl coenzyme A as cosubstrate. This modification reduces the cost of the method by at least one-half without sacrificing rapidity or accuracy.

Entities: Chemical

Mesh：

Substances：

Year: 1975 PMID： 1137391 PMCID： PMC429141 DOI： 10.1128/AAC.7.3.374

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

6 in total

1. Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'.

Authors: S Okamoto; Y Suzuki
Journal: Nature Date: 1965-12-25 Impact factor: 49.962

2. The release of enzymes by osmotic shock from Escherichia coli in exponential phase.

Authors: N G Nossal; L A Heppel
Journal: J Biol Chem Date: 1966-07-10 Impact factor: 5.157

3. Enzymatic acetylation as a means of determining serum aminoglycoside concentrations.

Authors: M J Haas; J Davies
Journal: Antimicrob Agents Chemother Date: 1973-10 Impact factor: 5.191

4. Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor.

Authors: R Benveniste; J Davies
Journal: Biochemistry Date: 1971-05-11 Impact factor: 3.162

5. Relation between dose and levels of gentamicin in blood.

Authors: R E Winters; K D Litwack; W L Hewitt
Journal: J Infect Dis Date: 1971-12 Impact factor: 5.226

6. Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.

Authors: A L Smith; D H Smith
Journal: J Infect Dis Date: 1974-04 Impact factor: 5.226

6 in total

13 in total

1. Radioimmunoassay of iodinated tobramycin.

Authors: A Broughton; J E Strong; L K Pickering; G P Bodney
Journal: Antimicrob Agents Chemother Date: 1976-10 Impact factor: 5.191

2. Enzymatic adenylylation by aminoglycoside 4'-adenylytransferase and 2"-adenylyltransferase as a means of determining concentrations of aminoglycoside antibiotics in serum.

Authors: P Santanam; F H Kayser
Journal: Antimicrob Agents Chemother Date: 1976-10 Impact factor: 5.191

Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum.

1. Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'.

2. The release of enzymes by osmotic shock from Escherichia coli in exponential phase.

3. Enzymatic acetylation as a means of determining serum aminoglycoside concentrations.

4. Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor.

5. Relation between dose and levels of gentamicin in blood.

6. Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.

1. Radioimmunoassay of iodinated tobramycin.

2. Enzymatic adenylylation by aminoglycoside 4'-adenylytransferase and 2"-adenylyltransferase as a means of determining concentrations of aminoglycoside antibiotics in serum.

3. Radioimmunoassay of sisomicin.

4. Comparison of the latex agglutination inhibition assay for tobramycin with radioimmunoassay.

5. Inhibition of acetylating activity in an enzymatic assay for aminoglycoside antibiotics.

6. Quantitation of antibiotics using high-pressure liquid chromatography: tetracycline.

7. Measurement of amikacin in serum by a latex agglutination inhibition test.

8. Comparison of radioimmunoassay with a new immunofluorescent method (FIAX) for measuring tobramycin in serum.

9. UK-18,892: resistance to modification by aminoglycoside-inactivating enzymes.

10. Common plasmid specifying tobramycin resistance found in two enteric bacteria isolated from burn patients.