| Literature DB >> 11369247 |
Abstract
Polycystic kidney disease results from loss of function of either of two novel proteins, polycystin-1 or polycystin-2. Recent studies show that intracellular calcium signaling is important in kidney development, and define defects in this signaling pathway as the basis of cyst formation in polycystic kidney disease.Entities:
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Year: 2001 PMID: 11369247 DOI: 10.1016/s0960-9822(01)00193-2
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834