Literature DB >> 11355021

Cloning and sequencing of a novel human gene which encodes a putative hydroxylase.

C Iriyama1, S Matsuda, R Katsumata, M Hamaguchi.   

Abstract

Using a conventional two-hybrid technique with MAWD as bait protein, a novel full-length cDNA was isolated and sequenced from a human liver cDNA library. This cDNA consists of 2,575 base pairs and has a predicted open reading frame encoding 255 amino acids. Overall, it is similar to the catalytic enzyme PHZF, catalyzing the hydroxylation of phenazine-1-carboxylic acid to 2-hydroxyphenazine-1-carboxylic acid. Polymerase chain reaction-based mapping with both a monochromosomal hybrid panel and radiation hybrid cell panels placed the gene to human chromosome 10q21.1 near the marker D10S210.

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Year:  2001        PMID: 11355021     DOI: 10.1007/s100380170081

Source DB:  PubMed          Journal:  J Hum Genet        ISSN: 1434-5161            Impact factor:   3.172


  9 in total

1.  The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family.

Authors:  Petra Herde; Wulf Blankenfeldt
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-05-31

2.  MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.

Authors:  Dong-Mei Li; Jun Zhang; Wen-Mei Li; Jian-Tao Cui; Yuan-Ming Pan; Si-Qi Liu; Rui Xing; You-Yong Lu
Journal:  World J Gastroenterol       Date:  2013-05-14       Impact factor: 5.742

3.  Human homologues of a Borrelia T cell epitope associated with antibiotic-refractory Lyme arthritis.

Authors:  Elise E Drouin; Lisa Glickstein; William W Kwok; Gerald T Nepom; Allen C Steere
Journal:  Mol Immunol       Date:  2007-06-06       Impact factor: 4.407

4.  Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens.

Authors:  Wulf Blankenfeldt; Alexandre P Kuzin; Tatiana Skarina; Yuriy Korniyenko; Liang Tong; Peter Bayer; Petra Janning; Linda S Thomashow; Dmitri V Mavrodi
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-15       Impact factor: 11.205

5.  Next generation sequencing identifies mutations in Atonal homolog 7 (ATOH7) in families with global eye developmental defects.

Authors:  Kamron Khan; Clare V Logan; Martin McKibbin; Eamonn Sheridan; Nursel H Elçioglu; Ozlem Yenice; David A Parry; Narcis Fernandez-Fuentes; Zakia I A Abdelhamed; Ahmed Al-Maskari; James A Poulter; Moin D Mohamed; Ian M Carr; Joanne E Morgan; Hussain Jafri; Yasmin Raashid; Graham R Taylor; Colin A Johnson; Chris F Inglehearn; Carmel Toomes; Manir Ali
Journal:  Hum Mol Genet       Date:  2011-11-07       Impact factor: 6.150

6.  Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer.

Authors:  Dongmei Li; Jun Zhang; Yu Xi; Lei Zhang; Wenmei Li; Jiantao Cui; Rui Xing; Yuanmin Pan; Zemin Pan; Feng Li; Youyong Lu
Journal:  BMC Cancer       Date:  2015-09-15       Impact factor: 4.430

7.  Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1.

Authors:  Jiansong Wu; Qiang Niu; Jie Yuan; Xiaodan Xu; Liuxia Cao
Journal:  Exp Ther Med       Date:  2019-10-07       Impact factor: 2.447

8.  Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling.

Authors:  Fachao Zhi; Xinmei Zhao; Shengbo Chen; Hongbin Liu; Zhijun Li; Jingyi Tang; Bing Huang
Journal:  Cell Death Dis       Date:  2021-05-31       Impact factor: 8.469

9.  Decreased expression of PBLD correlates with poor prognosis and functions as a tumor suppressor in human hepatocellular carcinoma.

Authors:  Aimin Li; Qun Yan; Xinmei Zhao; Jietao Zhong; Haiyun Yang; Zhiqiang Feng; Yanlei Du; Yadong Wang; Zenan Wang; Hong Wang; Yongjian Zhou; Side Liu; Yuqiang Nie
Journal:  Oncotarget       Date:  2016-01-05
  9 in total

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