| Literature DB >> 11354360 |
S Narayanan1, S Vangapandu, R Jain.
Abstract
Regiospecific synthesis of 2,3-disubstituted-L-histidines and 2,3-disubstituted histamines starting from L-histidine methyl ester and histamine is reported. The key step involves homolytic free radical alkylation via silver catalyzed oxidative decarboxylation of alkylcarboxylic acids with ammonium persulfate.Entities:
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Year: 2001 PMID： 11354360 DOI： 10.1016/s0960-894x(01)00154-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823