Literature DB >> 11349086

Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans.

M Jertborn1, I Nordström, A Kilander, C Czerkinsky, J Holmgren.   

Abstract

The induction of immune responses to rectally administered recombinant cholera toxin B subunit (CTB) in humans was studied. Three immunizations induced high levels of CTB-specific antibody-secreting cells, particular of the immunoglobulin A isotype, in both rectum and peripheral blood. Antitoxin antibody responses in rectal secretions and serum were also found.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11349086      PMCID： PMC98479          DOI： 10.1128/IAI.69.6.4125-4128.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  20 in total

1.  Safety and immunogenicity of an oral recombinant cholera B subunit-whole cell vaccine in Swedish volunteers.

Authors:  M Jertborn; A M Svennerholm; J Holmgren
Journal:  Vaccine       Date:  1992       Impact factor: 3.641

2.  Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans.

Authors:  C Czerkinsky; A M Svennerholm; M Quiding; R Jonsson; J Holmgren
Journal:  Infect Immun       Date:  1991-03       Impact factor: 3.441

3.  Differences in immune responses induced by oral and rectal immunizations with Salmonella typhi Ty21a: evidence for compartmentalization within the common mucosal immune system in humans.

Authors:  A Kantele; M Häkkinen; Z Moldoveanu; A Lu; E Savilahti; R D Alvarez; S Michalek; J Mestecky
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

4.  A novel two colour ELISPOT assay. I. Simultaneous detection of distinct types of antibody-secreting cells.

Authors:  C Czerkinsky; Z Moldoveanu; J Mestecky; L A Nilsson; O Ouchterlony
Journal:  J Immunol Methods       Date:  1988-11-25       Impact factor: 2.303

5.  Saliva, breast milk, and serum antibody responses as indirect measures of intestinal immunity after oral cholera vaccination or natural disease.

Authors:  M Jertborn; A M Svennerholm; J Holmgren
Journal:  J Clin Microbiol       Date:  1986-08       Impact factor: 5.948

6.  A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells.

Authors:  C C Czerkinsky; L A Nilsson; H Nygren; O Ouchterlony; A Tarkowski
Journal:  J Immunol Methods       Date:  1983-12-16       Impact factor: 2.303

7.  Specific immune response in humans following rectal delivery of live typhoid vaccine.

Authors:  B D Forrest; D J Shearman; J T LaBrooy
Journal:  Vaccine       Date:  1990-06       Impact factor: 3.641

8.  Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory.

Authors:  M Quiding; I Nordström; A Kilander; G Andersson; L A Hanson; J Holmgren; C Czerkinsky
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

9.  Serologic differentiation between antitoxin responses to infection with Vibrio cholerae and enterotoxin-producing Escherichia coli.

Authors:  A M Svennerholm; J Holmgren; R Black; M Levine; M Merson
Journal:  J Infect Dis       Date:  1983-03       Impact factor: 5.226

Review 10.  Mucosal immunity and tolerance: relevance to vaccine development.

Authors:  C Czerkinsky; F Anjuere; J R McGhee; A George-Chandy; J Holmgren; M P Kieny; K Fujiyashi; J F Mestecky; V Pierrefite-Carle; C Rask; J B Sun
Journal:  Immunol Rev       Date:  1999-08       Impact factor: 12.988
View more
  19 in total

1.  Oral immunization with a recombinant malaria protein induces conformational antibodies and protects mice against lethal malaria.

Authors:  Lina Wang; Lukasz Kedzierski; Steven L Wesselingh; Ross L Coppel
Journal:  Infect Immun       Date:  2003-05       Impact factor: 3.441

2.  Cholera toxin B-subunit gene enhances mucosal immunoglobulin A, Th1-type, and CD8+ cytotoxic responses when coadministered intradermally with a DNA vaccine.

Authors:  Alba E Sanchez; Guillermo Aquino; Pedro Ostoa-Saloma; Juan P Laclette; Leticia Rocha-Zavaleta
Journal:  Clin Diagn Lab Immunol       Date:  2004-07

3.  Mucosal immunization with virus-like particles of simian immunodeficiency virus conjugated with cholera toxin subunit B.

Authors:  Sang-Moo Kang; Qizhi Yao; Lizheng Guo; Richard W Compans
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

4.  Induction and distribution of intestinal immune responses after administration of recombinant cholera toxin B subunit in the ileal pouches of colectomized patients.

Authors:  J Kilhamn; H Brevinge; M Quiding-Järbrink; A M Svennerholm; M Jertborn
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

5.  Intrarectal immunization with rotavirus 2/6 virus-like particles induces an antirotavirus immune response localized in the intestinal mucosa and protects against rotavirus infection in mice.

Authors:  Davide Agnello; Christine A Hervé; Amandine Lavaux; Magali Darniot; Patrice Guillon; Annie Charpilienne; Pierre Pothier
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

6.  Binding efficiencies of carbohydrate ligands with different genotypes of cholera toxin B: molecular modeling, dynamics and docking simulation studies.

Authors:  Mobashar Hussain Urf Turabe Fazil; Sunil Kumar; Rohit Farmer; Haushila Prasad Pandey; Durg Vijai Singh
Journal:  J Mol Model       Date:  2011-03-16       Impact factor: 1.810

Review 7.  Microneedle and mucosal delivery of influenza vaccines.

Authors:  Sang-Moo Kang; Jae-Min Song; Yeu-Chun Kim
Journal:  Expert Rev Vaccines       Date:  2012-05       Impact factor: 5.217

8.  Kinetics of immune responses to influenza virus-like particles and dose-dependence of protection with a single vaccination.

Authors:  Fu Shi Quan; Dae-Goon Yoo; Jae-Min Song; John D Clements; Richard W Compans; Sang-Moo Kang
Journal:  J Virol       Date:  2009-02-11       Impact factor: 5.103

9.  Influence of exogenous reproductive hormones on specific antibody production in genital secretions after vaginal vaccination with recombinant cholera toxin B subunit in humans.

Authors:  Lotta Wassen; Marianne Jertborn
Journal:  Clin Vaccine Immunol       Date:  2006-02

10.  Sublingual vaccination with influenza virus protects mice against lethal viral infection.

Authors:  Joo-Hye Song; Huan H Nguyen; Nicolas Cuburu; Taisuke Horimoto; Sung-Youl Ko; Se-Ho Park; Cecil Czerkinsky; Mi-Na Kweon
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-28       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.