| Literature DB >> 11348195 |
C W West1, M A Estiarte, D H Rich.
Abstract
[reaction: see text]. Cysteine sulfhydryl protection with either the Fmoc or the Fm group was accomplished in one step and in high yield using commercially available FmocCl or FmocOSu, respectively. Mechanisms for the Fmoc to Fm transformations are discussed. Additionally, Fmoc-Cys(Fmoc)-OH (7) was synthesized and used in amide bond forming reactions. The S-Fmoc group is cleaved selectively from peptides containing the N-Fmoc group.Entities:
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Year: 2001 PMID： 11348195 DOI： 10.1021/ol015678d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005