Literature DB >> 11345500

Role of ETS family transcription factors in vascular development and angiogenesis.

Y Sato1.   

Abstract

The ETS family of transcription factors is defined by a conserved DNA-binding ETS domain that forms a winged helix-turn-helix structural motif. This family of transcription factors is involved in a diverse array of biological functions including cellular growth and differentiation, as well as organ development. Among the members of this family, ETS-1, ERG, Fli-1, TEL, and NERF-2 are expressed in endothelial cells and their progenitors. This review will summarize the role of ETS family transcription factors in vascular development and angiogenesis.

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Year:  2001        PMID： 11345500     DOI： 10.1247/csf.26.19

Source DB:  PubMed          Journal:  Cell Struct Funct        ISSN： 0386-7196            Impact factor:   2.212


  47 in total

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