Literature DB >> 11343920

Continuous recycling: a mechanism for modulatory signal transduction.

B C Freeman1, K R Yamamoto.   

Abstract

Modulatory signal transduction commonly requires efficient "on demand" assembly of specific multicomponent cellular machines that convert signals to cellular actions. This article suggests that for these signaling machines to detect and respond to fluctuations in signal strength, they must be continuously disassembled in an energy-dependent process that probably involves molecular chaperones.

Mesh：

Substances：

Year:  2001        PMID： 11343920     DOI： 10.1016/s0968-0004(01)01834-5

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  25 in total

1.  Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function.

Authors:  Paolo Ciana; Elisabetta Vegeto; Miguel Beato; Pierre Chambon; Jan-Ake Gustafsson; Malcolm Parker; Walter Wahli; Adriana Maggi
Journal:  EMBO Rep       Date:  2002-02       Impact factor: 8.807

2.  Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cells.

Authors:  Natalie E Simpson; Jason Gertz; Keren Imberg; Richard M Myers; Michael J Garabedian
Journal:  Mol Endocrinol       Date:  2011-11-10

3.  The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor.

Authors:  Liubov Shatkina; Sigrun Mink; Hermann Rogatsch; Helmut Klocker; Gernot Langer; Andrea Nestl; Andrew C B Cato
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

Review 4.  p23, a simple protein with complex activities.

Authors:  Sara J Felts; David O Toft
Journal:  Cell Stress Chaperones       Date:  2003       Impact factor: 3.667

5.  Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling.

Authors:  I Swameye; T G Muller; J Timmer; O Sandra; U Klingmuller
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-27       Impact factor: 11.205

6.  Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor.

Authors:  Neal D Freedman; Keith R Yamamoto
Journal:  Mol Biol Cell       Date:  2004-03-05       Impact factor: 4.138

7.  Corticosterone pretreatment suppresses stress-induced hypothalamic-pituitary-adrenal axis activity via multiple actions that vary with time, site of action, and de novo protein synthesis.

Authors:  Chad Osterlund; Robert L Spencer
Journal:  J Endocrinol       Date:  2011-01-04       Impact factor: 4.286

8.  Lysine deacetylases regulate the heat shock response including the age-associated impairment of HSF1.

Authors:  Elena Zelin; Brian C Freeman
Journal:  J Mol Biol       Date:  2015-02-15       Impact factor: 5.469

9.  The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly.

Authors:  Linda B Lingelbach; Kenneth B Kaplan
Journal:  Mol Cell Biol       Date:  2004-10       Impact factor: 4.272

10.  The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states.

Authors:  Diane C DeZwaan; Oyetunji A Toogun; Frank J Echtenkamp; Brian C Freeman
Journal:  Nat Struct Mol Biol       Date:  2009-06-14       Impact factor: 15.369
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