Literature DB >> 11332288

A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin.

M Matsuoka1, Y Kashiwabara, M Namisato.   

Abstract

Mycobacterium leprae were isolated from a Japanese patient, and susceptibility to antileprosy drugs was examined by the mouse foot pad method. The isolate was susceptible to clofazimine and clarithromycin, and resistant to dapsone, rifampin, ofloxacin and sparfloxacin. Mutations were identified in the genes associated with resistance to these drugs. The risk of the emergence of leprosy with multidrug resistance is emphasized.

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Year:  2000        PMID: 11332288

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN: 0148-916X


  30 in total

1.  Real-time PCR and high-resolution melt analysis for rapid detection of Mycobacterium leprae drug resistance mutations and strain types.

Authors:  Wei Li; Masanori Matsuoka; Masanori Kai; Pratibha Thapa; Saraswoti Khadge; Deanna A Hagge; Patrick J Brennan; Varalakshmi Vissa
Journal:  J Clin Microbiol       Date:  2011-12-14       Impact factor: 5.948

2.  Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America.

Authors:  Pushpendra Singh; Philippe Busso; Alberto Paniz-Mondolfi; Nacarid Aranzazu; Marc Monot; Nadine Honore; Andrea de Faria Fernandes Belone; Marcos Virmond; Maria Esther Villarreal-Olaya; Carlos Rivas; Stewart T Cole
Journal:  Antimicrob Agents Chemother       Date:  2011-03-28       Impact factor: 5.191

3.  Identification of primary drug resistance to rifampin in Mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil.

Authors:  Matilde Del Carmen Contreras Mejía; Maísa Porto Dos Santos; George Allan Villarouco da Silva; Isabella da Motta Passos; Felipe Gomes Naveca; Maria da Graça Souza Cunha; Milton Ozório Moraes; Lucia de Paula
Journal:  J Clin Microbiol       Date:  2014-10-01       Impact factor: 5.948

4.  Evidence for Mycobacterium leprae Drug Resistance in a Large Cohort of Leprous Neuropathy Patients from India.

Authors:  Niranjan Prakash Mahajan; Mallika Lavania; Itu Singh; Saraswati Nashi; Veeramani Preethish-Kumar; Seena Vengalil; Kiran Polavarapu; Chevula Pradeep-Chandra-Reddy; Muddasu Keerthipriya; Anita Mahadevan; Tagaduru Chickabasaviah Yasha; Bevinahalli Nanjegowda Nandeesh; Krishnamurthy Gnanakumar; Gareth J Parry; Utpal Sengupta; Atchayaram Nalini
Journal:  Am J Trop Med Hyg       Date:  2020-03       Impact factor: 2.345

5.  Amino acid substitutions at position 95 in GyrA can add fluoroquinolone resistance to Mycobacterium leprae.

Authors:  Kazumasa Yokoyama; Hyun Kim; Tetsu Mukai; Masanori Matsuoka; Chie Nakajima; Yasuhiko Suzuki
Journal:  Antimicrob Agents Chemother       Date:  2011-11-21       Impact factor: 5.191

Review 6.  Advances and hurdles on the way toward a leprosy vaccine.

Authors:  Malcolm S Duthie; Thomas P Gillis; Steven G Reed
Journal:  Hum Vaccin       Date:  2011-11-01

7.  Transmission of dapsone-resistant leprosy detected by molecular epidemiological approaches.

Authors:  Wei Li; Rama M Sakamuri; Danielle E Lyons; Florenda M Orcullo; Vidyagouri Shinde; Edred Lao Dela Pena; Armi A Maghanoy; Irene B Mallari; Esterlina V Tan; Indira Nath; Patrick J Brennan; Marivic Balagon; Varalakshmi Vissa
Journal:  Antimicrob Agents Chemother       Date:  2011-08-22       Impact factor: 5.191

Review 8.  Mycobacterium leprae: genes, pseudogenes and genetic diversity.

Authors:  Pushpendra Singh; Stewart T Cole
Journal:  Future Microbiol       Date:  2011-01       Impact factor: 3.165

9.  Vaccination with the ML0276 antigen reduces local inflammation but not bacterial burden during experimental Mycobacterium leprae infection.

Authors:  Vanitha S Raman; Joanne O'Donnell; H Remy Bailor; Wakako Goto; Ramanuj Lahiri; Thomas P Gillis; Steven G Reed; Malcolm S Duthie
Journal:  Infect Immun       Date:  2009-09-28       Impact factor: 3.441

10.  Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission.

Authors:  Masanori Matsuoka; Liangfen Zhang; Teky Budiawan; Keisuke Saeki; Shinzo Izumi
Journal:  J Clin Microbiol       Date:  2004-02       Impact factor: 5.948

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