Literature DB >> 11329597

Significance of the clinical course and early upper gastrointestinal studies in predicting complications associated with repair of esophageal atresia.

N L Yanchar1, R Gordon, M Cooper, H Dunlap, P Soucy.   

Abstract

BACKGROUND/
PURPOSE: In many centers, use of upper gastrointestinal (UGI) contrast studies in the early postoperative period after esophageal atresia (EA) repair is considered routine. Indications for this are many, including searching for existing problems and predicting future complications. However, most major complications, both early and late, usually are identified clinically before any radiologic studies. The purpose of this study was to investigate factors that may anticipate the development of postoperative complications after EA repair, looking particularly at the predictive value of routine early postoperative UGI studies.
METHODS: A total of 111 consecutive cases of EA were identified retrospectively over a 10-year period from 2 major Canadian pediatric health centers. One hundred one were associated with a distal tracheoesophageal fistula (TEF), of which, 90 had repairs. Ninety-seven percent of these had a UGI study at a median of 9.1 postoperative days (range, 2 to 23) before consideration of oral feeding. Charts were reviewed looking at patient variables, surgical factors, early UGI findings, and postoperative courses. Complications that required intervention were noted, including anastomotic leaks, gastroesophageal reflux (GER), strictures, and recurrent and missed fistulae. All initial UGI studies were reexamined by 1 of 2 pediatric radiologists. Logistic regression was used to examine relationships between these clinical and radiologic variables and outcomes.
RESULTS: Of the variables analyzed, univariate analysis showed clinically significant leaks to be associated with intraoperative factors (subjective degree of anastomotic tension, and the use of myotomies) and early postoperative clinical evidence suggesting a leak. In a multivariate model, all remained independently significant except for the use of myotomies. Later development of clinically significant GER also was associated with the degree of tension. It had no relationship, however, with findings of dysmotility, esophageal shortening, or reflux at the initial UGI study. Development of a stricture requiring dilatations or resection was associated with a history of clinically evident GER only; no relationships were seen with a history of an anastomotic leak or any other clinical, operative, or radiographic variables. Missed or recurrent fistulae were all suspected clinically before radiologic confirmation.
CONCLUSIONS: Early and late complications after repair of EA can be identified and potentially anticipated based on clinical findings at the time of repair and during the postoperative period. The use of early "routine" UGI studies, with no suspicion of a problem, has little value in terms of predicting complications or future clinical course. Copyright 2001 by W.B. Saunders Company.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11329597     DOI: 10.1053/jpsu.2001.22969

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  10 in total

1.  Recurrent tracheoesophageal fistula after thoracoscopic repair: vanishing clips as a potential sign.

Authors:  Alan E Schlesinger; Mark V Mazziotti; Christopher I Cassady; Ashwin P Pimpalwar
Journal:  Pediatr Surg Int       Date:  2011-04-24       Impact factor: 1.827

2.  Novel use of porcine extracellular matrix in recurrent stricture following repair of tracheoesophageal fistula.

Authors:  Sarah B Cairo; Benjamin Tabak; Carroll M Harmon; Kathryn D Bass
Journal:  Pediatr Surg Int       Date:  2017-07-29       Impact factor: 1.827

Review 3.  Thoracoscopic surgery for esophageal atresia.

Authors:  George W Holcomb
Journal:  Pediatr Surg Int       Date:  2017-01-07       Impact factor: 1.827

Review 4.  The management of postoperative reflux in congenital esophageal atresia-tracheoesophageal fistula: a systematic review.

Authors:  Anna C Shawyer; Joanne D'Souza; Julia Pemberton; Helene Flageole
Journal:  Pediatr Surg Int       Date:  2014-07-11       Impact factor: 1.827

5.  Thoracoscopic repair of esophageal atresia and tracheoesophageal fistula: a multi-institutional analysis.

Authors:  George W Holcomb; Steven S Rothenberg; Klaas M A Bax; Marcelo Martinez-Ferro; Craig T Albanese; Daniel J Ostlie; David C van Der Zee; C K Yeung
Journal:  Ann Surg       Date:  2005-09       Impact factor: 12.969

6.  Radiation exposure in infants with oesophageal atresia and tracheo-oesophageal fistula.

Authors:  Kiera Roberts; Jonathan Karpelowsky; Dominic A Fitzgerald; Soundappan S V Soundappan
Journal:  Pediatr Surg Int       Date:  2019-02-01       Impact factor: 1.827

7.  Does postoperative pH monitoring predict complicated gastroesophageal reflux in patients with esophageal atresia?

Authors:  A Koivusalo; M Pakarinen; R J Rintala; H Lindahl
Journal:  Pediatr Surg Int       Date:  2004-09-11       Impact factor: 1.827

8.  Predictive factors affecting the prognosis and late complications of 73 consecutive cases of esophageal atresia at 2 centers.

Authors:  Ryuta Masuya; Tatsuru Kaji; Motoi Mukai; Kazuhiko Nakame; Takafumi Kawano; Seiro Machigashira; Waka Yamada; Koji Yamada; Shun Onishi; Keisuke Yano; Tomoe Moriguchi; Koshiro Sugita; Masato Kawano; Hiroyuki Noguchi; Masaya Suzuhigashi; Mitsuru Muto; Satoshi Ieiri
Journal:  Pediatr Surg Int       Date:  2018-08-06       Impact factor: 1.827

9.  Respiratory problems in children with esophageal atresia and tracheoesophageal fistula.

Authors:  Federica Porcaro; Laura Valfré; Lelia Rotondi Aufiero; Luigi Dall'Oglio; Paola De Angelis; Alberto Villani; Pietro Bagolan; Sergio Bottero; Renato Cutrera
Journal:  Ital J Pediatr       Date:  2017-09-05       Impact factor: 2.638

Review 10.  Eosinophilic Esophagitis in Esophageal Atresia.

Authors:  Usha Krishnan
Journal:  Front Pediatr       Date:  2019-11-29       Impact factor: 3.418

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.