Literature DB >> 11329053

The cellular neurobiology of depression.

H K Manji1, W C Drevets, D S Charney.   

Abstract

Major depressive disorders, long considered to be of neurochemical origin, have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways may hold promise as new therapeutics for depression.

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Year:  2001        PMID: 11329053     DOI: 10.1038/87865

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  279 in total

1.  Serotonin receptors modulate GABA(A) receptor channels through activation of anchored protein kinase C in prefrontal cortical neurons.

Authors:  J Feng; X Cai; J Zhao; Z Yan
Journal:  J Neurosci       Date:  2001-09-01       Impact factor: 6.167

Review 2.  Regulation of GABAergic inhibition by serotonin signaling in prefrontal cortex: molecular mechanisms and functional implications.

Authors:  Zhen Yan
Journal:  Mol Neurobiol       Date:  2002 Oct-Dec       Impact factor: 5.590

3.  CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli.

Authors:  Michel Barrot; Jocelien D A Olivier; Linda I Perrotti; Ralph J DiLeone; Olivier Berton; Amelia J Eisch; Soren Impey; Daniel R Storm; Rachael L Neve; Jerry C Yin; Venetia Zachariou; Eric J Nestler
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-06       Impact factor: 11.205

4.  Effects of antidepressant drug imipramine on gene expression in rat prefrontal cortex.

Authors:  Juha E A Knuuttila; Petri Törönen; Eero Castrén
Journal:  Neurochem Res       Date:  2004-06       Impact factor: 3.996

5.  Extracellular signal-regulated kinase 2 signaling in the hippocampal dentate gyrus mediates the antidepressant effects of testosterone.

Authors:  Nicole Carrier; Mohamed Kabbaj
Journal:  Biol Psychiatry       Date:  2012-01-20       Impact factor: 13.382

Review 6.  Sigma receptors: potential targets for a new class of antidepressant drug.

Authors:  James A Fishback; Matthew J Robson; Yan-Tong Xu; Rae R Matsumoto
Journal:  Pharmacol Ther       Date:  2010-05-11       Impact factor: 12.310

7.  Chronic variable stress impairs energy metabolism in prefrontal cortex and hippocampus of rats: prevention by chronic antioxidant treatment.

Authors:  Bárbara Tagliari; Cristie G Noschang; Andréia G K Ferreira; Otávio A Ferrari; Luciane R Feksa; Clovis M D Wannmacher; Carla Dalmaz; Angela T S Wyse
Journal:  Metab Brain Dis       Date:  2010-05-27       Impact factor: 3.584

8.  BDNF val66met polymorphism, white matter abnormalities and remission of geriatric depression.

Authors:  George S Alexopoulos; Charles E Glatt; Matthew J Hoptman; Dora Kanellopoulos; Christopher F Murphy; Robert E Kelly; Sarah S Morimoto; Kelvin O Lim; Faith M Gunning
Journal:  J Affect Disord       Date:  2010-03-25       Impact factor: 4.839

Review 9.  Reconsidering anhedonia in depression: lessons from translational neuroscience.

Authors:  Michael T Treadway; David H Zald
Journal:  Neurosci Biobehav Rev       Date:  2010-07-11       Impact factor: 8.989

Review 10.  HCN Channel Targets for Novel Antidepressant Treatment.

Authors:  Stacy M Ku; Ming-Hu Han
Journal:  Neurotherapeutics       Date:  2017-07       Impact factor: 7.620

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