Literature DB >> 1132802

The effect of intravenous infusions of prostaglandins E-2 and F-2alpha on human gastric function.

A Newman, J P de Moraes-Filho, D Philippakos, J J Misiewicz.   

Abstract

The effect of intravenous infusions of prostaglandins E-2 and F(-2alpha) at various dose levels on basal, or on maximally or submaximally pentagastrin-stimulated acid secretion, was studied in 40 male subjects. Intraluminal antral pressures were also measured. Prostaglandin F (0.08 mug kg-minus 1 min-minus 1) transiently, but significantly, inhibited submaximal acid output and increased the frequency of antral contractions. Prostaglandin E(2)(0.08 mug kg-minus 1 min-minus 1) inhibited basal acid secretion.

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Year:  1975        PMID: 1132802      PMCID: PMC1410922          DOI: 10.1136/gut.16.4.272

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  21 in total

1.  A COMPARISON OF THE ACTIONS OF PROSTAGLANDINS F2-ALPHA AND E1 ON SMOOTH MUSCLE.

Authors:  E W HORTON; I H MAIN
Journal:  Br J Pharmacol Chemother       Date:  1965-04

2.  Occurrence of prostaglandin E2 in the human stomach, and a study of its effects on human isolated gastric muscle.

Authors:  A Bennett; J G Murray; J H Wyllie
Journal:  Br J Pharmacol Chemother       Date:  1968

3.  Comparison of prostaglandin E1 and norepinephrine on the gastric mucosal circulation.

Authors:  E D Jacobson
Journal:  Proc Soc Exp Biol Med       Date:  1970-02

4.  Relative activity of prostaglandins E1, A1, E2 and A2 on lipolysis, platelet aggregation, smooth muscle and the cardiovascular system.

Authors:  J R Weeks; N C Sekhar; D W Ducharme
Journal:  J Pharm Pharmacol       Date:  1969-02       Impact factor: 3.765

5.  Inhibition of gastric acid secretion in vitro by prostaglandin E1.

Authors:  L Way; R P Durbin
Journal:  Nature       Date:  1969-03-01       Impact factor: 49.962

6.  Effect of intravenous prostaglandin F 2 on small intestinal function in man.

Authors:  J H Cummings; A Newman; J J Misiewicz; G J Milton-Thompson; J A Billings
Journal:  Nature       Date:  1973-05-18       Impact factor: 49.962

7.  The effect of prostaglandin E1 on the secretion and the motility of the human stomach.

Authors:  M Classen; P Stürzenhofecker; H Koch; L Demling
Journal:  Acta Hepatogastroenterol (Stuttg)       Date:  1973 Mar-Apr

8.  Interaction of prostaglandins with blood plasma proteins. I. Binding of prostaglandin E 2 to human plasma proteins and its effect on the physiological activity of prostaglandin E 2 in vitro and in vivo.

Authors:  A Raz
Journal:  Biochim Biophys Acta       Date:  1972-12-08

9.  Inhibition by prostaglandin E 1 of gastric secretion in the dog.

Authors:  J E Nezamis; A Robert; D F Stowe
Journal:  J Physiol       Date:  1971-10       Impact factor: 5.182

10.  Prostaglandin E2 and gastric acid secretion in man.

Authors:  A Bennett; I F Stamford; W G Unger
Journal:  J Physiol       Date:  1973-03       Impact factor: 5.182

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  9 in total

1.  Exogenous prostaglandins and gastric secretion in the cat.

Authors:  R Baker; B M Jaffe; J D Reed; B Shaw; C W Venables
Journal:  J Physiol       Date:  1978-05       Impact factor: 5.182

2.  The effect of 15(R)-15-methyl prostaglandin E2 on meal-stimulated gastric acid secretion, serum gastrin, and pancreatic polypeptide in duodenal ulcer patients.

Authors:  W Peterson; M Feldman; I Taylor; M Bremer
Journal:  Dig Dis Sci       Date:  1979-05       Impact factor: 3.199

3.  Hypertrophic gastritis associated with increased gastric mucosal prostaglandin E2 concentrations in a patient with the carcinoid syndrome.

Authors:  E J Boyd; G Hulks; J S Thomas; K E McColl
Journal:  Gut       Date:  1988-09       Impact factor: 23.059

4.  Effects of prostaglandin E2 on gastric acid secretory function and ulcerogenesis induced by different methods (experimental study).

Authors:  V H Vasilenko; A L Grebenev; E N Kochina; L S Grebeneva; L A Poloschenkova; L I Tsvetkova
Journal:  Gastroenterol Jpn       Date:  1978

5.  Oral antisecretory activity of prostaglandin E2 in man.

Authors:  S B Reele; D Bohan
Journal:  Dig Dis Sci       Date:  1984-05       Impact factor: 3.199

6.  Gastric antisecretory activity of arbaprostil as affected by gastric pH.

Authors:  S B Reele
Journal:  Dig Dis Sci       Date:  1985-07       Impact factor: 3.199

7.  Effects of aspirin and prostaglandin E2 on interdigestive motility complex and duodenogastric reflux in man.

Authors:  C P Dooley; W D Mello; J E Valenzuela
Journal:  Dig Dis Sci       Date:  1985-06       Impact factor: 3.199

8.  Prevention of aspirin-induced faecal blood loss by prostaglandin E2.

Authors:  M M Cohen; G Cheung; D M Lyster
Journal:  Gut       Date:  1980-07       Impact factor: 23.059

9.  Endogenous prostaglandins in peptic ulcer disease.

Authors:  R Baker; B M Jaffe; C W Venables
Journal:  Gut       Date:  1979-05       Impact factor: 23.059

  9 in total

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