Literature DB >> 11310819

Hepatitis C virus transmission in a pediatric oncology ward: analysis of an outbreak and review of the literature.

A Knöll1, M Helmig, O Peters, W Jilg.   

Abstract

Hospital-related hepatitis C virus (HCV) infections continue to occur even after the introduction of blood donor screening. We report an outbreak of HCV in nine patients of a pediatric oncology ward in 1996/1997. Sequencing of the hypervariable genomic region 1 (HVR1) of the E2/NS1 region showed near identity between HCV isolates from these patients as evidence for infection with the same virus. Despite a detailed and careful investigation, the source of infection and the mode of virus transmission could not be established. Based on a review of the current literature about nosocomial HCV infection and HCV infection in children, hypotheses for possible means of transmission in this outbreak are discussed.

Entities:  

Mesh：

Year:  2001        PMID： 11310819     DOI： 10.1038/labinvest.3780234

Source DB:  PubMed          Journal:  Lab Invest        ISSN： 0023-6837            Impact factor:   5.662


  8 in total

1.  Prevalence and clinical presentations of hepatitis C virus among patients admitted to the rheumatology ward.

Authors:  Ayman El Garf; Bassel El Zorkany; Rasha Gheith; Hala Sheba; Geilan Abdel Moneim; Kamal El Garf
Journal:  Rheumatol Int       Date:  2011-07-27       Impact factor: 2.631

Review 2.  Health care-associated hepatitis C virus infection.

Authors:  Bruno Pozzetto; Meriam Memmi; Olivier Garraud; Xavier Roblin; Philippe Berthelot
Journal:  World J Gastroenterol       Date:  2014-12-14       Impact factor: 5.742

Review 3.  Managing occupational risks for hepatitis C transmission in the health care setting.

Authors:  David K Henderson
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

4.  Use of the minimum spanning tree model for molecular epidemiological investigation of a nosocomial outbreak of hepatitis C virus infection.

Authors:  Enea Spada; Luciano Sagliocca; John Sourdis; Anna Rosa Garbuglia; Vincenzo Poggi; Carmela De Fusco; Alfonso Mele
Journal:  J Clin Microbiol       Date:  2004-09       Impact factor: 5.948

5.  Mitogen-activated protein kinase signalling pathways triggered by the hepatitis C virus envelope protein E2: implications for the prevention of infection.

Authors:  L-J Zhao; P Zhao; Q-L Chen; H Ren; W Pan; Z-T Qi
Journal:  Cell Prolif       Date:  2007-08       Impact factor: 6.831

6.  [Requirements for hygiene in the medical care of immunocompromised patients. Recommendations from the Committee for Hospital Hygiene and Infection Prevention at the Robert Koch Institute (RKI)].

Authors: 
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2010-04       Impact factor: 1.513

7.  The role of hemodialysis machines dedication in reducing Hepatitis C transmission in the dialysis setting in Iran: a multicenter prospective interventional study.

Authors:  Alireza Abdollah Shamshirsaz; Mohammad Kamgar; Mir Reza Bekheirnia; Farzam Ayazi; Seyed Reza Hashemi; Navid Bouzari; Mohammad Reza Habibzadeh; Nima Pourzahedgilani; Varshasb Broumand; Amir Hooshang Abdollah Shamshirsaz; Maziyar Moradi; Mehrdad Borghei; Niloofar Nobakht Haghighi; Behrooz Broumand
Journal:  BMC Nephrol       Date:  2004-10-07       Impact factor: 2.388

8.  Modeling suggests that microliter volumes of contaminated blood caused an outbreak of hepatitis C during computerized tomography.

Authors:  Eyal Shteyer; Louis Shekhtman; Tal Zinger; Sheri Harari; Inna Gafanovich; Dana Wolf; Hefziba Ivgi; Rima Barsuk; Ilana Dery; Daniela Armoni; Mila Rivkin; Rahul Pipalia; Michal Cohen Eliav; Yizhak Skorochod; Gabriel S Breuer; Ran Tur-Kaspa; Yonit Weil Wiener; Adi Stern; Scott J Cotler; Harel Dahari; Yoav Lurie
Journal:  PLoS One       Date:  2019-01-15       Impact factor: 3.240
  8 in total

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