Literature DB >> 11304171

An improved method for the palladium-catalyzed amination of aryl iodides.

M H Ali1, S L Buchwald.   

Abstract

Aryl iodides are coupled with amines to give the corresponding arylamines in high yield in the presence of palladium, a suitable ligand, and NaOt-Bu. Functionalized aryl iodides give good yields of the corresponding arylamines when Cs(2)CO(3) is substituted as the base.

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Year:  2001        PMID： 11304171     DOI： 10.1021/jo0008486

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  10 in total

1.  Solution-phase parallel synthesis of a multi-substituted benzo[b]thiophene library.

Authors:  Chul-Hee Cho; Benjamin Neuenswander; Gerald H Lushington; Richard C Larock
Journal:  J Comb Chem       Date:  2009 Sep-Oct

2.  Palladium-catalyzed coupling of ammonia with aryl chlorides, bromides, iodides, and sulfonates: a general method for the preparation of primary arylamines.

Authors:  Giang D Vo; John F Hartwig
Journal:  J Am Chem Soc       Date:  2009-08-12       Impact factor: 15.419

Review 3.  Biaryl phosphane ligands in palladium-catalyzed amination.

Authors:  David S Surry; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  Highly reactive, general and long-lived catalysts for palladium-catalyzed amination of heteroaryl and aryl chlorides, bromides, and iodides: scope and structure-activity relationships.

Authors:  Qilong Shen; Tokutaro Ogata; John F Hartwig
Journal:  J Am Chem Soc       Date:  2008-04-30       Impact factor: 15.419

5.  Studies on high-temperature amination reactions of aromatic chlorides using discrete palladium-N-heterocyclic carbene (NHC) complexes and in situ palladium/imidazolium salt protocols.

Authors:  Andrew J McCarroll; David A Sandham; Lisa R Titcomb; Alexandra K de K Lewis; F Geoffrey N Cloke; Brian P Davies; Alejandro Perez de Santana; Wolfgang Hiller; Stephen Caddick
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

6.  An efficient process for pd-catalyzed C-N cross-coupling reactions of aryl iodides: insight into controlling factors.

Authors:  Brett P Fors; Nicole R Davis; Stephen L Buchwald
Journal:  J Am Chem Soc       Date:  2009-04-29       Impact factor: 15.419

7.  Parallel synthesis of a multi-substituted benzo[b]furan library.

Authors:  Chul-Hee Cho; Benjamin Neuenswander; Gerald H Lushington; Richard C Larock
Journal:  J Comb Chem       Date:  2008-10-21

8.  [(CyPF-(t)Bu)PdCl2]: an air-stable, one-component, highly efficient catalyst for amination of heteroaryl and aryl halides.

Authors:  Qilong Shen; John F Hartwig
Journal:  Org Lett       Date:  2008-08-21       Impact factor: 6.005

9.  A general, efficient, and functional-group-tolerant catalyst system for the palladium-catalyzed thioetherification of aryl bromides and iodides.

Authors:  Manuel A Fernández-Rodríguez; John F Hartwig
Journal:  J Org Chem       Date:  2009-02-20       Impact factor: 4.354

10.  Solution-phase parallel synthesis of a multisubstituted cyclic imidate library.

Authors:  Saurabh Mehta; Jesse P Waldo; Benjamin Neuenswander; Gerald H Lushington; Richard C Larock
Journal:  ACS Comb Sci       Date:  2013-04-04       Impact factor: 3.784
  10 in total

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