Literature DB >> 11293367

Why does schizophrenia develop at late adolescence?

C Harrop1, P Trower.   

Abstract

Schizophrenia is one of the most researched, yet still one of the least understood, of the mental disorders. One key area that remains comparatively neglected is the fact that schizophrenia typically develops at late adolescence. In common with people with psychotic disorders, around 25% of normal teenagers also report finding adolescence very distressing, and a substantial empirical literature shows that certain characteristics typical of adolescence such as conflicted family relationships, grandiosity, egocentrism, and magical ideation bear a distinct resemblance to phenomena seen in psychotic disorders. Indeed, such phenomena, as might be judged prodromal or symptomatic in first-onset schizophrenia, have been shown to be remarkably common in normal adolescents, generally in about 50% of samples. Furthermore, prodromal-like signs in normal adolescents appear to be functionally linked to psychological development. For most adolescents, such phenomena pass with successful psychological development. It is proposed that psychosis in late adolescence is a consequence of severe disruption in this normally difficult psychological maturational process in vulnerable individuals, and explanations are offered as to why and how this comes about. It is suggested that problems either in reaching psychological maturity with regard to parents or in bonding to peers or both, may lead to crucial self-construction difficulties, and that psychosis emerges out of such "blocked adolescence." This approach proposes therapeutic interventions that enable professional services to side with both parents and clients simultaneously, and is normalizing and stigma-free.

Entities:  

Mesh:

Year:  2001        PMID: 11293367     DOI: 10.1016/s0272-7358(99)00047-1

Source DB:  PubMed          Journal:  Clin Psychol Rev        ISSN: 0272-7358


  20 in total

Review 1.  The development of schizophrenia in late adolescence.

Authors:  Chris E Harrop
Journal:  Curr Psychiatry Rep       Date:  2002-08       Impact factor: 5.285

2.  The Subjective Experience of Youth Psychotropic Treatment.

Authors:  Jerry Floersch
Journal:  Soc Work Ment Health       Date:  2004-03-01

3.  Life events and suicidality in adolescents with schizophrenia.

Authors:  Silvana Fennig; Netta Horesh; Daphna Aloni; Alan Apter; Abraham Weizman; Shmuel Fennig
Journal:  Eur Child Adolesc Psychiatry       Date:  2005-12       Impact factor: 4.785

4.  Self-determination and first-episode psychosis: associations with symptomatology, social and vocational functioning, and quality of life.

Authors:  Nicholas J K Breitborde; Petra Kleinlein; Vinod H Srihari
Journal:  Schizophr Res       Date:  2012-03-22       Impact factor: 4.939

5.  A survey of psychosis risk symptoms in Kenya.

Authors:  Daniel Mamah; Anne Mbwayo; Victoria Mutiso; Deanna M Barch; John N Constantino; Thelma Nsofor; Lincoln Khasakhala; David M Ndetei
Journal:  Compr Psychiatry       Date:  2011-09-25       Impact factor: 3.735

Review 6.  Adolescence as a period of vulnerability and intervention in schizophrenia: Insights from the MAM model.

Authors:  Felipe V Gomes; Millie Rincón-Cortés; Anthony A Grace
Journal:  Neurosci Biobehav Rev       Date:  2016-05-24       Impact factor: 8.989

7.  Exposure to kynurenic acid during adolescence produces memory deficits in adulthood.

Authors:  Cynthia O Akagbosu; Gretchen C Evans; Danielle Gulick; Raymond F Suckow; David J Bucci
Journal:  Schizophr Bull       Date:  2010-12-20       Impact factor: 9.306

8.  Administration of kynurenine during adolescence, but not during adulthood, impairs social behavior in rats.

Authors:  Katelyn V Trecartin; David J Bucci
Journal:  Schizophr Res       Date:  2011-09-09       Impact factor: 4.939

9.  The experiences of inpatient nursing staff caring for young people with early psychosis.

Authors:  Jessica Thompson; Zoe Vr Boden; Elizabeth K Newton; Kelly Fenton; Gareth Hickman; Michael Larkin
Journal:  J Res Nurs       Date:  2019-03-05

10.  The 'at-risk mental state' for psychosis in adolescents: clinical presentation, transition and remission.

Authors:  Patrick Welsh; Paul A Tiffin
Journal:  Child Psychiatry Hum Dev       Date:  2014-02
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