| Literature DB >> 11291599 |
M C Toufektsian1, F R Boucher, S Tanguy, S Morel, J G de Leiris.
Abstract
Oxygen-derived free radicals (O2.-, H2O2, and .OH) that are produced during postischemic reperfusion are currently suspected to be involved in the pathogenesis of tissue injury. Another reactive oxygen species, the electronically excited molecular oxygen (1O2), is of increasing interest in the area of experimental research in cardiology. In this review are discussed the main potential sources of singlet oxygen in the organism, particularly in the myocardium, the various cardiovascular cytotoxic effects induced by this reactive oxygen intermediate, and the growing evidence of its involvement in ischemia/reperfusion injury.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11291599 DOI: 10.1089/152308601750100506
Source DB: PubMed Journal: Antioxid Redox Signal ISSN: 1523-0864 Impact factor: 8.401