Literature DB >> 11291013

Neuropsychiatric implications and long-term consequences of fetal alcohol spectrum disorders.

A P Streissguth1, K O'Malley.   

Abstract

Prenatal alcohol exposure can cause a whole spectrum of central nervous system (CNS) sequelae that persist throughout the life span and manifest in a spectrum of effects from clinically indistinguishable to severely impairing. The greatest impact of alcohol as a teratogen is to the brain-the greatest need is for holistic treatment and management of the associated mental disorders. The interaction of this subtle brain damage with the complex psychosocial circumstances surrounding the birth of a child to a mother with alcohol problems can further compound development and result in costly and devastating social consequences. Research is urgently needed on the chronic neuropsychiatric sequelae of these subtle birth defects of the brain. Identification of these fetal alcohol spectrum disorders (FASD) in the psychiatric nomenclature is a necessary step to focus the attention and resources of the mental health field on this personally and socially significant problem.

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Mesh:

Year:  2000        PMID: 11291013     DOI: 10.1053/scnp.2000.6729

Source DB:  PubMed          Journal:  Semin Clin Neuropsychiatry        ISSN: 1084-3612


  102 in total

Review 1.  Classical eyeblink conditioning: clinical models and applications.

Authors:  J E Steinmetz; J A Tracy; J T Green
Journal:  Integr Physiol Behav Sci       Date:  2001 Jul-Sep

2.  A limited access mouse model of prenatal alcohol exposure that produces long-lasting deficits in hippocampal-dependent learning and memory.

Authors:  Megan L Brady; Andrea M Allan; Kevin K Caldwell
Journal:  Alcohol Clin Exp Res       Date:  2011-09-20       Impact factor: 3.455

3.  Choline supplementation and DNA methylation in the hippocampus and prefrontal cortex of rats exposed to alcohol during development.

Authors:  Nicha K H Otero; Jennifer D Thomas; Christopher A Saski; Xiaoxia Xia; Sandra J Kelly
Journal:  Alcohol Clin Exp Res       Date:  2012-04-17       Impact factor: 3.455

4.  Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats.

Authors:  Kristina A Uban; Joanna H Sliwowska; Stephanie Lieblich; Linda A Ellis; Wayne K Yu; Joanne Weinberg; Liisa A M Galea
Journal:  Horm Behav       Date:  2010-08-22       Impact factor: 3.587

5.  Neurobehavioral Deficits Consistent Across Age and Sex in Youth with Prenatal Alcohol Exposure.

Authors:  Amy L Panczakiewicz; Leila Glass; Claire D Coles; Julie A Kable; Elizabeth R Sowell; Jeffrey R Wozniak; Kenneth Lyons Jones; Edward P Riley; Sarah N Mattson
Journal:  Alcohol Clin Exp Res       Date:  2016-07-19       Impact factor: 3.455

6.  Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD.

Authors:  Hani El Shawa; Charles W Abbott; Kelly J Huffman
Journal:  J Neurosci       Date:  2013-11-27       Impact factor: 6.167

7.  Prenatal Alcohol Exposure Leads to Enhanced Serine 9 Phosphorylation of Glycogen Synthase Kinase-3β (GSK-3β) in the Hippocampal Dentate Gyrus of Adult Mouse.

Authors:  Lee Anna Cunningham; Jessie Newville; Lu Li; Phillip Tapia; Andrea M Allan; C Fernando Valenzuela
Journal:  Alcohol Clin Exp Res       Date:  2017-10-03       Impact factor: 3.455

8.  Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus.

Authors:  Megan L Brady; Marvin R Diaz; Anthony Iuso; Julie C Everett; C Fernando Valenzuela; Kevin K Caldwell
Journal:  J Neurosci       Date:  2013-01-16       Impact factor: 6.167

9.  Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation.

Authors:  Yunlong Liu; Yokesh Balaraman; Guohua Wang; Kenneth P Nephew; Feng C Zhou
Journal:  Epigenetics       Date:  2009-10-01       Impact factor: 4.528

10.  Binge-like postnatal alcohol exposure triggers cortical gliogenesis in adolescent rats.

Authors:  Jennifer L Helfer; Lyngine H Calizo; Willie K Dong; Charles R Goodlett; William T Greenough; Anna Y Klintsova
Journal:  J Comp Neurol       Date:  2009-05-20       Impact factor: 3.215

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