Literature DB >> 11279517

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci.

W O Cookson1, B Ubhi, R Lawrence, G R Abecasis, A J Walley, H E Cox, R Coleman, N I Leaves, R C Trembath, M F Moffatt, J I Harper.   

Abstract

We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.

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Year:  2001        PMID： 11279517     DOI： 10.1038/86867

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  51 in total

Review 1.  Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins.

Authors:  Camille A Knosp; James A Johnston
Journal:  Immunology       Date:  2012-02       Impact factor: 7.397

Review 2.  Eczema in early life: genetics, the skin barrier, and lessons learned from birth cohort studies.

Authors:  Jocelyn M Biagini Myers; Gurjit K Khurana Hershey
Journal:  J Pediatr       Date:  2010-08-24       Impact factor: 4.406

Review 3.  Epidermal barrier formation and recovery in skin disorders.

Authors:  Julia A Segre
Journal:  J Clin Invest       Date:  2006-05       Impact factor: 14.808

4.  Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis.

Authors:  E Ekelund; A Saaf; M Tengvall-Linder; E Melen; J Link; J Barker; N J Reynolds; S J Meggitt; J Kere; C-F Wahlgren; G Pershagen; M Wickman; M Nordenskjold; I Kockum; M Bradley
Journal:  Am J Hum Genet       Date:  2006-04-14       Impact factor: 11.025

Review 5.  Epigenetic regulation of skin: focus on the Polycomb complex.

Authors:  Jisheng Zhang; Evan S Bardot; Elena Ezhkova
Journal:  Cell Mol Life Sci       Date:  2012-07       Impact factor: 9.261

6.  Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response.

Authors:  Ali R Djalilian; David McGaughey; Satyakam Patel; Eun Young Seo; Chenghua Yang; Jun Cheng; Melanija Tomic; Satrajit Sinha; Akemi Ishida-Yamamoto; Julia A Segre
Journal:  J Clin Invest       Date:  2006-04-20       Impact factor: 14.808

Review 7.  Cutaneous perspectives on adaptive immunity.

Authors:  Michael Girardi
Journal:  Clin Rev Allergy Immunol       Date:  2007-10       Impact factor: 8.667

Review 8.  Psoriasis: advances in pathophysiology and management.

Authors:  A MacDonald; A D Burden
Journal:  Postgrad Med J       Date:  2007-11       Impact factor: 2.401

9.  A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis.

Authors:  Cristina de Guzman Strong; Sean Conlan; Clayton B Deming; Jun Cheng; Karen E Sears; Julia A Segre
Journal:  Hum Mol Genet       Date:  2010-01-20       Impact factor: 6.150

10.  Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21.

Authors:  Ulla Christensen; Steffen Møller-Larsen; Mette Nyegaard; Annette Haagerup; Anne Hedemand; Charlotte Brasch-Andersen; Torben A Kruse; Thomas Juhl Corydon; Mette Deleuran; Anders D Børglum
Journal:  Hum Genet       Date:  2009-06-11       Impact factor: 4.132
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