Literature DB >> 11266083

Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race.

C M Stein1, C C Lang, H G Xie, A J Wood.   

Abstract

Hypertension is more frequent and more severe in some Black populations. Although many studies have focused on hypertension in black people in an attempt to understand the genetic and environmental factors that regulate blood pressure, this approach has not been productive. Study of the relationship between specific phenotypes and genotypes, both within and across ethnic groups, is more likely to advance our understanding of the regulation of blood pressure than studies focused on race and blood pressure.

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Year:  2001        PMID: 11266083     DOI: 10.1097/00008571-200103000-00001

Source DB:  PubMed          Journal:  Pharmacogenetics        ISSN: 0960-314X


  11 in total

Review 1.  Novel treatment approaches in hypertensive type 2 diabetic patients.

Authors:  Yaniel Castro Torres; Richard E Katholi
Journal:  World J Diabetes       Date:  2014-08-15

2.  Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.

Authors:  Daniel Kurnik; Eitan A Friedman; Mordechai Muszkat; Gbenga G Sofowora; Hong-Guang Xie; William D Dupont; Alastair J J Wood; C Michael Stein
Journal:  Pharmacogenet Genomics       Date:  2008-09       Impact factor: 2.089

3.  GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.

Authors:  Daniel Kurnik; Andrew J Cunningham; Gbenga G Sofowora; Utkarsh Kohli; Chun Li; Eitan A Friedman; Mordechai Muszkat; Usha B Menon; Alastair Jj Wood; C Michael Stein
Journal:  Pharmacogenomics       Date:  2009-10       Impact factor: 2.533

4.  Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.

Authors:  Daniel Kurnik; Chun Li; Gbenga G Sofowora; Eitan A Friedman; Mordechai Muszkat; Hong-Guang Xie; Paul A Harris; Scott M Williams; Usha B Nair; Alastair J J Wood; C Michael Stein
Journal:  Pharmacogenet Genomics       Date:  2008-10       Impact factor: 2.089

5.  Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial.

Authors:  Vibha Bhatnagar; Daniel T O'Connor; Nicholas J Schork; Rany M Salem; Caroline M Nievergelt; Brinda K Rana; Douglas W Smith; George L Bakris; John P Middleton; Keith C Norris; Jackson T Wright; Deanna Cheek; Leena Hiremath; Gabriel Contreras; Lawrence J Appel; Michael S Lipkowitz
Journal:  J Hypertens       Date:  2007-10       Impact factor: 4.844

6.  Endothelial nitric oxide synthase gene polymorphisms and the risk of acute myocardial infarction in a South Indian population.

Authors:  Annan Sudarsan Arun Kumar; Gurusamy Umamaheswaran; Ramamoorthy Padmapriya; Jayaraman Balachandar; Chandrasekaran Adithan
Journal:  Mol Biol Rep       Date:  2012-10-29       Impact factor: 2.316

7.  Blacks have a greater sensitivity to α1-adrenoceptor-mediated venoconstriction compared with whites.

Authors:  Abiodun Adefurin; Laxmi V Ghimire; Utkarsh Kohli; Mordechai Muszkat; Gbenga G Sofowora; Sachin Y Paranjape; C Michael Stein; Daniel Kurnik
Journal:  Hypertension       Date:  2013-02-11       Impact factor: 10.190

8.  Frequency of eNOS polymorphisms in the Colombian general population.

Authors:  Norma C Serrano; Luis A Díaz; Juan P Casas; Aroon D Hingorani; Daniel Moreno de Lucca; María C Páez
Journal:  BMC Genet       Date:  2010-06-20       Impact factor: 2.797

9.  Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy.

Authors:  Ayhan Olcay; C Gokhan Ekmekci; Ugur Ozbek; Murat Sezer; Cem Barcin; Erol Arslan; Bilal Boztosun; Yilmaz Nisanci
Journal:  Cardiovasc Ultrasound       Date:  2006-08-21       Impact factor: 2.062

10.  Extensive ethnogenomic diversity of endothelial nitric oxide synthase (eNOS) polymorphisms.

Authors:  Bolaji N Thomas; Tanya J Thakur; Li Yi; Aldiouma Guindo; Dapa A Diallo; Jurg Ott
Journal:  Gene Regul Syst Bio       Date:  2013-01-15
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