Literature DB >> 11263489

Proteolysis in Alzheimer's disease. Can plasmin tip the balance?

G Periz1, M E Fortini.   

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Year:  2000        PMID： 11263489      PMCID： PMC1083794          DOI： 10.1093/embo-reports/kvd124

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


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  16 in total

Review 1.  Abeta-generating enzymes: recent advances in beta- and gamma-secretase research.

Authors:  R Vassar; M Citron
Journal:  Neuron       Date:  2000-09       Impact factor: 17.173

2.  Binding of disease-associated prion protein to plasminogen.

Authors:  M B Fischer; C Roeckl; P Parizek; H P Schwarz; A Aguzzi
Journal:  Nature       Date:  2000-11-23       Impact factor: 49.962

3.  Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.

Authors:  G Yu; M Nishimura; S Arawaka; D Levitan; L Zhang; A Tandon; Y Q Song; E Rogaeva; F Chen; T Kawarai; A Supala; L Levesque; H Yu; D S Yang; E Holmes; P Milman; Y Liang; D M Zhang; D H Xu; C Sato; E Rogaev; M Smith; C Janus; Y Zhang; R Aebersold; L S Farrer; S Sorbi; A Bruni; P Fraser; P St George-Hyslop
Journal:  Nature       Date:  2000-09-07       Impact factor: 49.962

4.  Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice.

Authors:  R Madani; S Hulo; N Toni; H Madani; T Steimer; D Muller; J D Vassalli
Journal:  EMBO J       Date:  1999-06-01       Impact factor: 11.598

Review 5.  Intracellular APP processing and A beta production in Alzheimer disease.

Authors:  C A Wilson; R W Doms; V M Lee
Journal:  J Neuropathol Exp Neurol       Date:  1999-08       Impact factor: 3.685

6.  Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.

Authors:  S Parvathy; I Hussain; E H Karran; A J Turner; N M Hooper
Journal:  Biochemistry       Date:  1999-07-27       Impact factor: 3.162

7.  Linguistic ability in early life and the neuropathology of Alzheimer's disease and cerebrovascular disease. Findings from the Nun Study.

Authors:  D A Snowdon; L H Greiner; W R Markesbery
Journal:  Ann N Y Acad Sci       Date:  2000-04       Impact factor: 5.691

8.  The plasmin system is induced by and degrades amyloid-beta aggregates.

Authors:  H M Tucker; M Kihiko; J N Caldwell; S Wright; T Kawarabayashi; D Price; D Walker; S Scheff; J P McGillis; R E Rydel; S Estus
Journal:  J Neurosci       Date:  2000-06-01       Impact factor: 6.167

9.  Plasmin cleavage of the amyloid beta-protein: alteration of secondary structure and stimulation of tissue plasminogen activator activity.

Authors:  W E Van Nostrand; M Porter
Journal:  Biochemistry       Date:  1999-08-31       Impact factor: 3.162

10.  A detergent-insoluble membrane compartment contains A beta in vivo.

Authors:  S J Lee; U Liyanage; P E Bickel; W Xia; P T Lansbury; K S Kosik
Journal:  Nat Med       Date:  1998-06       Impact factor: 53.440
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  5 in total

1.  Therapeutic potential and anti-amyloidosis mechanisms of tert-butylhydroquinone for Alzheimer's disease.

Authors:  Hasina Akhter; Ashwini Katre; Ling Li; Xuebo Liu; Rui-Ming Liu
Journal:  J Alzheimers Dis       Date:  2011       Impact factor: 4.472

Review 2.  Current concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer's disease.

Authors:  J Steven Jacobsen; Peter Reinhart; Menelas N Pangalos
Journal:  NeuroRx       Date:  2005-10

3.  Novel Combinatorial Therapeutic Targeting of PAI-1 (SERPINE1) Gene Expression in Alzheimer's Disease.

Authors:  Stacie M Kutz; Craig E Higgins; Paul J Higgins
Journal:  Mol Med Ther       Date:  2012-12-13

4.  Enhanced clearance of Abeta in brain by sustaining the plasmin proteolysis cascade.

Authors:  J Steven Jacobsen; Thomas A Comery; Robert L Martone; Hassan Elokdah; David L Crandall; Aram Oganesian; Suzan Aschmies; Yolanda Kirksey; Cathleen Gonzales; Jane Xu; Hua Zhou; Kevin Atchison; Erik Wagner; Margaret M Zaleska; Indranil Das; Robert L Arias; Jonathan Bard; David Riddell; Stephen J Gardell; Magid Abou-Gharbia; Albert Robichaud; Ronald Magolda; George P Vlasuk; Thorir Bjornsson; Peter H Reinhart; Menelas N Pangalos
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-16       Impact factor: 11.205

5.  The TGF-beta1/upstream stimulatory factor-regulated PAI-1 gene: potential involvement and a therapeutic target in Alzheimer's disease.

Authors:  Paul J Higgins
Journal:  J Biomed Biotechnol       Date:  2006
  5 in total

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