Literature DB >> 11259050

Enantioselective synthesis of epigallocatechin-3-gallate (EGCG), the active polyphenol component from green tea.

L Li1, T H Chan.   

Abstract

[reaction: see text]. Enantioselective synthesis of epigallocatechin-3-gallate (EGCG, 3b), the active polyphenol component from green tea, has been achieved by using a stereospecific cyclization of the Sharpless asymmetric dihydroxylation product 7c as the key step.

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Year:  2001        PMID： 11259050     DOI： 10.1021/ol000394z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  13 in total

1.  Synthesis and structure-activity relationships of EGCG analogues, a recently identified Hsp90 inhibitor.

Authors:  Anuj Khandelwal; Jessica A Hall; Brian S J Blagg
Journal:  J Org Chem       Date:  2013-08-01       Impact factor: 4.354

Review 2.  Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives.

Authors:  Dale G Nagle; Daneel Ferreira; Yu-Dong Zhou
Journal:  Phytochemistry       Date:  2006-07-31       Impact factor: 4.072

Review 3.  Perspectives on the recent developments with green tea polyphenols in drug discovery.

Authors:  Feng Li; Yongli Wang; Dapeng Li; Yilun Chen; Xuguang Qiao; Rania Fardous; Ashton Lewandowski; Jinbao Liu; Tak-Hang Chan; Q Ping Dou
Journal:  Expert Opin Drug Discov       Date:  2018-04-24       Impact factor: 6.098

4.  Synthesis of (2R, 3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, and evaluation of its proteasome inhibitory activities.

Authors:  Kumi Osanai; Congde Huo; Kristin R Landis-Piwowar; Q Ping Dou; Tak Hang Chan
Journal:  Tetrahedron       Date:  2007-08-06       Impact factor: 2.457

Review 5.  EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment.

Authors:  Di Chen; Sheng Biao Wan; Huanjie Yang; Jian Yuan; Tak Hang Chan; Q Ping Dou
Journal:  Adv Clin Chem       Date:  2011       Impact factor: 5.394

6.  Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors.

Authors:  Lei You; Eun Jeong Cho; John Leavitt; Li-Chung Ma; Gaetano T Montelione; Eric V Anslyn; Robert M Krug; Andrew Ellington; Jon D Robertus
Journal:  Bioorg Med Chem Lett       Date:  2011-03-17       Impact factor: 2.823

Review 7.  The challenge of developing green tea polyphenols as therapeutic agents.

Authors:  C Huo; S B Wan; W H Lam; L Li; Z Wang; K R Landis-Piwowar; D Chen; Q P Dou; T H Chan
Journal:  Inflammopharmacology       Date:  2008-10       Impact factor: 4.473

8.  Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase.

Authors:  Takashi Kuzuhara; Yuma Iwai; Hironobu Takahashi; Dai Hatakeyama; Noriko Echigo
Journal:  PLoS Curr       Date:  2009-10-13

9.  Design of an amide N-glycoside derivative of β-glucogallin: a stable, potent, and specific inhibitor of aldose reductase.

Authors:  Linfeng Li; Kun-Che Chang; Yaming Zhou; Biehuoy Shieh; Jessica Ponder; Adedoyin D Abraham; Hadi Ali; Anson Snow; J Mark Petrash; Daniel V LaBarbera
Journal:  J Med Chem       Date:  2013-12-23       Impact factor: 7.446

10.  Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs.

Authors:  Congde Huo; Huanjie Yang; Qiuzhi Cindy Cui; Q Ping Dou; Tak Hang Chan
Journal:  Bioorg Med Chem       Date:  2009-12-16       Impact factor: 3.641
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