| Literature DB >> 11257441 |
Abstract
The identification of gp95sortilin, a sorting protein, as being the 100 kDa neurotensin (NT) receptor, a non-G-protein coupled receptor, constitutes a new and interesting but intriguing step in the neuropeptide signaling as well as in cellular trafficking. The isolation of the same protein by three different experimental approaches sum up the complexity for researchers involved in the functional significance of the so-called sortilin/neurotensin receptor 3 (NTR3). This review will concentrate on the putative physiological and cellular roles of sortilin/NTR3 as most results so far have proposed hypothetical conclusions rather than concrete evidence.Entities:
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Year: 2001 PMID： 11257441 DOI： 10.1016/s0898-6568(00)00130-3
Source DB: PubMed Journal: Cell Signal ISSN： 0898-6568 Impact factor: 4.315