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Literature DB >> 24040621

Progranulin: a novel regulator of gastrointestinal cancer progression.

Abstract

Progranulin (PGRN) is a soluble factor that regulates cell proliferation, motility and inflammation. A role for PGRN in the progression of ovarian and breast cancers is well established. However, the expression and subsequent consequences of PGRN on the progression of gastrointestinal tumors is not well recognized. This review briefly summarizes our current knowledge of the mechanisms of action of PGRN and highlights the role of this signaling molecule in various gastrointestinal cancers.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Cholangiocarcinoma; colorectal cancer; esophageal cancer; growth factor; hepatocellular carcinoma

Year: 2013 PMID： 24040621 PMCID： PMC3770304 DOI： 10.3978/j.issn.2224-4778.2013.02.02

Source DB: PubMed Journal: Transl Gastrointest Cancer ISSN： 2224-476X

48 in total

Review 1. Peripheral cholangiocarcinoma (cholangiocellular carcinoma): clinical features, diagnosis and treatment.

Authors: M F Chen
Journal: J Gastroenterol Hepatol Date: 1999-12 Impact factor: 4.029

Review 2. Cellular effects of progranulin in health and disease.

Authors: Louis De Muynck; Philip Van Damme
Journal: J Mol Neurosci Date: 2011-05-25 Impact factor: 3.444

3. Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.

Authors: Xiaoling Xu; Shogo Kobayashi; Wenhui Qiao; Cuiling Li; Cuiying Xiao; Svetlana Radaeva; Bangyan Stiles; Rui-Hong Wang; Nobuya Ohara; Tadashi Yoshino; Derek LeRoith; Michael S Torbenson; Gregory J Gores; Hong Wu; Bin Gao; Chu-Xia Deng
Journal: J Clin Invest Date: 2006-06-08 Impact factor: 14.808

4. Biliary infections: spectrum of imaging findings and management.

Authors: Onofrio A Catalano; Dushyant V Sahani; David G Forcione; Benedikt Czermak; Chang-Hsien Liu; Andrea Soricelli; Ronald S Arellano; Peter R Muller; Peter F Hahn
Journal: Radiographics Date: 2009-11 Impact factor: 5.333

5. Expression of PC cell-derived growth factor and vascular endothelial growth factor in esophageal squamous cell carcinoma and their clinicopathologic significance.

Authors: Xiang-yu Chen; Jian-sheng Li; Qian-ping Liang; De-zhi He; Jing Zhao
Journal: Chin Med J (Engl) Date: 2008-05-20 Impact factor: 2.628

Review 6. The interactomics of sortilin: an ancient lysosomal receptor evolving new functions.

Authors: Maryssa Canuel; Yuan Libin; Carlos R Morales
Journal: Histol Histopathol Date: 2009-04 Impact factor: 2.303

7. Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival.

Authors: Zhiheng He; Amin Ismail; Leonid Kriazhev; Gulzhakhan Sadvakassova; Andrew Bateman
Journal: Cancer Res Date: 2002-10-01 Impact factor: 12.701

8. Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding.

Authors: Georgina S Butler; Richard A Dean; Eric M Tam; Christopher M Overall
Journal: Mol Cell Biol Date: 2008-05-27 Impact factor: 4.272

Review 9. Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis.

Authors: Zhiheng He; Andrew Bateman
Journal: J Mol Med (Berl) Date: 2003-08-19 Impact factor: 4.599

10. Structure and chromosomal location of the human granulin gene.

Authors: V Bhandari; A Bateman
Journal: Biochem Biophys Res Commun Date: 1992-10-15 Impact factor: 3.575

14 in total

1. Identification of a mitochondrial defect gene signature reveals NUPR1 as a key regulator of liver cancer progression.

Authors: Young-Kyoung Lee; Byul A Jee; So Mee Kwon; Young-Sil Yoon; Wei Guang Xu; Hee-Jung Wang; Xin Wei Wang; Snorri S Thorgeirsson; Jae-Seon Lee; Hyun Goo Woo; Gyesoon Yoon
Journal: Hepatology Date: 2015-08-07 Impact factor: 17.425

2. The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels.

Authors: Amanda R Mason; Lisa P Elia; Steven Finkbeiner
Journal: J Biol Chem Date: 2017-01-09 Impact factor: 5.157

3. Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis.

Authors: Akio Kimura; Masao Takemura; Ginette Serrero; Nobuaki Yoshikura; Yuichi Hayashi; Kuniaki Saito; Takashi Inuzuka
Journal: J Neurooncol Date: 2018-01-16 Impact factor: 4.130

Review 4. The role of progranulin in diabetes and kidney disease.

Authors: Bruna Bellincanta Nicoletto; Luis Henrique Canani
Journal: Diabetol Metab Syndr Date: 2015-12-21 Impact factor: 3.320

Review 5. From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes.

Authors: Hae-Ok Byun; Young-Kyoung Lee; Jeong-Min Kim; Gyesoon Yoon
Journal: BMB Rep Date: 2015-10 Impact factor: 4.778