Literature DB >> 11256569

Genetics and molecular genetics of the MHC.

D A Rhodes1, J Trowsdale.   

Abstract

The MHC is a well-characterised region of the human genome, containing a high diversity of genes and an apparent clustering of genes involved in the immune response. The genomic sequence of an 8 Mb section, containing the MHC and flanking regions and covering over 300 genes, will soon be available. Since this is a highly polymorphic region, the molecular genetics of the MHC and its relationship with disease have been studied in considerable detail.

Entities:  

Mesh：

Year:  1999        PMID： 11256569

Source DB:  PubMed          Journal:  Rev Immunogenet        ISSN： 1398-1714


  14 in total

1.  PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data.

Authors:  Alex Lancaster; Mark P Nelson; Diogo Meyer; Richard M Single; Glenys Thomson
Journal:  Pac Symp Biocomput       Date:  2003

2.  Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients.

Authors:  Roberto Herrera-Goepfert; Jesus-K Yamamoto-Furusho; Luis-F Onate-Ocana; Margarita Camorlinga-Ponce; Leopoldo Munoz; Jorge-A Ruiz-Morales; Gilberto Vargas-Alarcon; Julio Granados
Journal:  World J Gastroenterol       Date:  2006-12-28       Impact factor: 5.742

3.  Major histocompatibility complex and alveolar epithelial apoptosis in idiopathic pulmonary fibrosis.

Authors:  Ramcés Falfán-Valencia; Angel Camarena; Armida Juárez; Carina Becerril; Martha Montaño; José Cisneros; Felipe Mendoza; Julio Granados; Annie Pardo; Moisés Selman
Journal:  Hum Genet       Date:  2005-11-15       Impact factor: 4.132

4.  The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients.

Authors:  E Lindholm; E Bakhtadze; M Sjögren; C M Cilio; E Agardh; L Groop; C-D Agardh
Journal:  Diabetologia       Date:  2006-09-13       Impact factor: 10.122

Review 5.  Human leukocyte antigen gene polymorphism and the histocompatibility laboratory.

Authors:  T M Williams
Journal:  J Mol Diagn       Date:  2001-08       Impact factor: 5.568

Review 6.  RAGE: a novel target for drug intervention in diabetic vascular disease.

Authors:  Barry I Hudson; Ann Marie Schmidt
Journal:  Pharm Res       Date:  2004-07       Impact factor: 4.200

7.  Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.

Authors:  Robert R Graham; Ward A Ortmann; Carl D Langefeld; Damini Jawaheer; Scott A Selby; Peter R Rodine; Emily C Baechler; Kristine E Rohlf; Katherine B Shark; Karl J Espe; Linda E Green; Rajan P Nair; Philip E Stuart; James T Elder; Richard A King; Kathy L Moser; Patrick M Gaffney; Teodorica L Bugawan; Henry A Erlich; Stephen S Rich; Peter K Gregersen; Timothy W Behrens
Journal:  Am J Hum Genet       Date:  2002-07-26       Impact factor: 11.025

8.  Patterned variation in murine MHC promoters.

Authors:  N Avrion Mitchison; Jurgen Roes
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-19       Impact factor: 11.205

9.  Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Authors:  Robert R Graham; Chieko Kyogoku; Snaevar Sigurdsson; Irina A Vlasova; Leela R L Davies; Emily C Baechler; Robert M Plenge; Thearith Koeuth; Ward A Ortmann; Geoffrey Hom; Jason W Bauer; Clarence Gillett; Noel Burtt; Deborah S Cunninghame Graham; Robert Onofrio; Michelle Petri; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Gunnel Nordmark; Peter K Gregersen; Kathy Moser; Patrick M Gaffney; Lindsey A Criswell; Timothy J Vyse; Ann-Christine Syvänen; Paul R Bohjanen; Mark J Daly; Timothy W Behrens; David Altshuler
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-05       Impact factor: 11.205

10.  Genetic meta-analysis of cancer diagnosis following statin use identifies new associations and implicates human leukocyte antigen (HLA) in women.

Authors:  Jean-Claude Tardif; Marie-Pierre Dubé; Maxine Sun; Audrey Lemaçon; Marc-André Legault; Géraldine Asselin; Sylvie Provost; Hugues Aschard; Amina Barhdadi; Yassamin Feroz Zada; Diane Valois; Ian Mongrain
Journal:  Pharmacogenomics J       Date:  2021-03-01       Impact factor: 3.550
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