| Literature DB >> 11254650 |
A Qamar1, S Aboudola, M Warny, P Michetti, C Pothoulakis, J T LaMont, C P Kelly.
Abstract
Saccharomyces boulardii is a nonpathogenic yeast that protects against antibiotic-associated diarrhea and recurrent Clostridium difficile colitis. The administration of C. difficile toxoid A by gavage to S. boulardii-fed BALB/c mice caused a 1.8-fold increase in total small intestinal immunoglobulin A levels (P = 0.003) and a 4.4-fold increase in specific intestinal anti-toxin A levels (P < 0.001). Enhancing host intestinal immune responses may be an important mechanism for S. boulardii-mediated protection against diarrheal illnesses.Entities:
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Year: 2001 PMID： 11254650 PMCID： PMC98222 DOI： 10.1128/IAI.69.4.2762-2765.2001
Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441