Literature DB >> 11253127

Antioxidants in health and disease.

I S Young1, J V Woodside.   

Abstract

Free radical production occurs continuously in all cells as part of normal cellular function. However, excess free radical production originating from endogenous or exogenous sources might play a role in many diseases. Antioxidants prevent free radical induced tissue damage by preventing the formation of radicals, scavenging them, or by promoting their decomposition. This article reviews the basic chemistry of free radical formation in the body, the consequences of free radical induced tissue damage, and the function of antioxidant defence systems, with particular reference to the development of atherosclerosis.

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Year:  2001        PMID： 11253127      PMCID： PMC1731363          DOI： 10.1136/jcp.54.3.176

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  130 in total

Review 1.  Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions.

Authors:  P Libby; G K Hansson
Journal:  Lab Invest       Date:  1991-01       Impact factor: 5.662

Review 2.  Role of free radicals and catalytic metal ions in human disease: an overview.

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Journal:  Methods Enzymol       Date:  1990       Impact factor: 1.600

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Authors:  K Kugiyama; S A Kerns; J D Morrisett; R Roberts; P D Henry
Journal:  Nature       Date:  1990-03-08       Impact factor: 49.962

4.  Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.

Authors:  R Stocker; V W Bowry; B Frei
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

5.  Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene.

Authors:  R A Riemersma; D A Wood; C C Macintyre; R A Elton; K F Gey; M F Oliver
Journal:  Lancet       Date:  1991-01-05       Impact factor: 79.321

6.  Rate constants for quenching singlet oxygen and activities for inhibiting lipid peroxidation of carotenoids and alpha-tocopherol in liposomes.

Authors:  K Fukuzawa; Y Inokami; A Tokumura; J Terao; A Suzuki
Journal:  Lipids       Date:  1998-08       Impact factor: 1.880

7.  The antioxidant butylated hydroxytoluene protects against atherosclerosis.

Authors:  I Björkhem; A Henriksson-Freyschuss; O Breuer; U Diczfalusy; L Berglund; P Henriksson
Journal:  Arterioscler Thromb       Date:  1991 Jan-Feb

8.  Effect of selenium deficiency on cellular and extracellular glutathione peroxidases: immunochemical detection and mRNA analysis in rat kidney and serum.

Authors:  T Nakane; K Asayama; K Kodera; H Hayashibe; N Uchida; S Nakazawa
Journal:  Free Radic Biol Med       Date:  1998-09       Impact factor: 7.376

9.  Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein.

Authors:  I Jialal; G L Vega; S M Grundy
Journal:  Atherosclerosis       Date:  1990-06       Impact factor: 5.162

10.  Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

Authors:  S Ylä-Herttuala; W Palinski; M E Rosenfeld; S Parthasarathy; T E Carew; S Butler; J L Witztum; D Steinberg
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808
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  265 in total

1.  A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys.

Authors:  Erik K Kastman; Auriel A Willette; Christopher L Coe; Barbara B Bendlin; Kris J Kosmatka; Donald G McLaren; Guofan Xu; Elisa Canu; Aaron S Field; Andrew L Alexander; Mary Lou Voytko; T Mark Beasley; Ricki J Colman; Richard H Weindruch; Sterling C Johnson
Journal:  J Neurosci       Date:  2010-06-09       Impact factor: 6.167

2.  Effect of Radiofrequency on DNA Damage and Oxidative Status in Patients with Turbinate Hypertrophy.

Authors:  Erol Senturk; Selahattin Tugrul; Remzi Doğan; Sabri Baki Eren; Orhan Ozturan; Abdurrahim Koçyiğit; Sıddıka Kesgin
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2017-08-04

3.  Oxidant/antioxidant status in men with Behçet's disease.

Authors:  Seyithan Taysi; Berna Demircan; Necmettin Akdeniz; Mustafa Atasoy; Refik Ali Sari
Journal:  Clin Rheumatol       Date:  2007-01-06       Impact factor: 2.980

4.  Variation of antioxidant activity and phenolic content of some common home remedies with storage time.

Authors:  Shaik Rahiman; Bilal Ahmad Tantry; Avneesh Kumar
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-10-01

Review 5.  Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases.

Authors:  Ivona Brasnjevic; Patrick R Hof; Harry W M Steinbusch; Christoph Schmitz
Journal:  DNA Repair (Amst)       Date:  2008-05-23

6.  Assessment of Oxidant-Antioxidant Status and Stress Factor in Recurrent Aphthous Stomatitis Patients: Case Control Study.

Authors:  Sherin Ziaudeen; Rathy Ravindran
Journal:  J Clin Diagn Res       Date:  2017-03-01

7.  Association between optimism and serum antioxidants in the midlife in the United States study.

Authors:  Julia K Boehm; David R Williams; Eric B Rimm; Carol Ryff; Laura D Kubzansky
Journal:  Psychosom Med       Date:  2012-12-20       Impact factor: 4.312

8.  Relation of plasma protein oxidation parameters and paraoxonase activity in the ageing population.

Authors:  Ufuk Cakatay; Refik Kayali; Hafize Uzun
Journal:  Clin Exp Med       Date:  2008-04-03       Impact factor: 3.984

9.  Brain effect of insulin and clonazepam in diabetic rats under depressive-like behavior.

Authors:  Carlos Alberto Yasin Wayhs; Caroline Paula Mescka; Camila Simioni Vanzin; Graziela Schmitt Ribas; Gilian Guerreiro; Maurício Schüler Nin; Vanusa Manfredini; Helena Maria Tannhauser Barros; Carmen Regla Vargas
Journal:  Metab Brain Dis       Date:  2013-03-27       Impact factor: 3.584

10.  Low total antioxidative capacity levels are associated with augmentation index but not pulse-wave velocity.

Authors:  Omer Gedikli; Serkan Ozturk; Hulya Yilmaz; Merih Baykan; Abdulkadir Kiris; Ismet Durmus; Kayhan Karaman; Caner Karahan; Sukru Celik
Journal:  Heart Vessels       Date:  2009-09-27       Impact factor: 2.037
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