Literature DB >> 11252000

Recurrent trisomy 15 in a female carrier of der(15)t(Y;15)(q12;p13).

E Rajcan-Separovic1, W P Robinson, M Stephenson, T Pantzar, L Arbour, D McFadden, J Guscott.   

Abstract

We report on a female carrier of der(15) t(Y;15)(q12;p13) who had two pregnancy losses with trisomy 15 and one with tetraploidy. Molecular analysis showed that both non-disjunction events resulting in the trisomy 15 pregnancies occurred in maternal meiosis I. This finding raises the possibility that there may be an increased risk for trisomy 15 in some carriers of unbalanced t(Y;15) which, if followed by trisomic zygote rescue, may lead to uniparental disomy (UPD). Copyright 2001 Wiley-Liss, Inc.

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Year:  2001        PMID： 11252000     DOI： 10.1002/1096-8628(2001)9999:9999<::aid-ajmg1173>3.0.co;2-1

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN： 0148-7299


  4 in total

1.  A normal birth following preimplantation genetic diagnosis by FISH determination in the carriers of der(15)t(Y;15)(Yq12;15p11) translocations: two case reports.

Authors:  Yongjian Chen; Guian Chen; Ying Lian; Xuefeng Gao; Jin Huang; Jie Qiao
Journal:  J Assist Reprod Genet       Date:  2007-08-29       Impact factor: 3.412

2.  The origin of abnormalities in recurrent aneuploidy/polyploidy.

Authors:  W P Robinson; D E McFadden; M D Stephenson
Journal:  Am J Hum Genet       Date:  2001-10-23       Impact factor: 11.025

3.  46,XX, der(15),t(Y;15)(q12;p11) karyotype in an azoospermic male.

Authors:  Serap T Onrat; Zafer Söylemez; Muhsin Elmas
Journal:  Indian J Hum Genet       Date:  2012-05

4.  Prenatal diagnosis of the maternal derivative chromosome der(15)t(Y;15)(q12;p13) in a dizygotic twin pregnancy.

Authors:  Pei-Yi Chen; Jui-Hung Yen; Ching-Feng Cheng; Pao Chu Chen; Yi-Shian Li; Tzu-Ying Li; Chung-Nan Yeh; Jye-Siung Fang
Journal:  Ci Ji Yi Xue Za Zhi       Date:  2016-07-02
  4 in total

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