Literature DB >> 11250205

Familial and sporadic primary pulmonary hypertension is caused by BMPR2 gene mutations resulting in haploinsufficiency of the bone morphogenetic protein tùype II receptor.

J Thomson1, R Machado, M Pauciulo, N Morgan, M Yacoub, P Corris, K McNeil, J Loyd, W Nichols, R Trembath.   

Abstract

Entities:  

Year:  2001        PMID： 11250205     DOI： 10.1016/s1053-2498(01)00259-5

Source DB:  PubMed          Journal:  J Heart Lung Transplant        ISSN： 1053-2498            Impact factor:   10.247


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  13 in total

1.  Patchy deletion of Bmpr1a potentiates proximal pulmonary artery remodeling in mice exposed to chronic hypoxia.

Authors:  Rebecca R Vanderpool; Nesrine El-Bizri; Marlene Rabinovitch; Naomi C Chesler
Journal:  Biomech Model Mechanobiol       Date:  2013-01

Review 2.  Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer.

Authors:  Barbara Jung; Jonas J Staudacher; Daniel Beauchamp
Journal:  Gastroenterology       Date:  2016-10-20       Impact factor: 22.682

Review 3.  Signaling Receptors for TGF-β Family Members.

Authors:  Carl-Henrik Heldin; Aristidis Moustakas
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-08-01       Impact factor: 10.005

4.  Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension.

Authors:  Rachel Damico; Todd M Kolb; Lidenys Valera; Lan Wang; Traci Housten; Ryan J Tedford; David A Kass; Nicholas Rafaels; Li Gao; Kathleen C Barnes; Raymond L Benza; James L Rand; Rizwan Hamid; James E Loyd; Ivan M Robbins; Anna R Hemnes; Wendy K Chung; Eric D Austin; M Bradley Drummond; Stephen C Mathai; Paul M Hassoun
Journal:  Am J Respir Crit Care Med       Date:  2015-01-15       Impact factor: 21.405

5.  Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

Authors:  Kwon-Ho Hong; Young Jae Lee; Eunji Lee; Sung Ok Park; Chul Han; Hideyuki Beppu; En Li; Mohan K Raizada; Kenneth D Bloch; S Paul Oh
Journal:  Circulation       Date:  2008-07-28       Impact factor: 29.690

6.  Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling.

Authors:  Nesrine El-Bizri; Lingli Wang; Sandra L Merklinger; Christophe Guignabert; Tushar Desai; Takashi Urashima; Ahmad Y Sheikh; Russell H Knutsen; Robert P Mecham; Yuji Mishina; Marlene Rabinovitch
Journal:  Circ Res       Date:  2007-12-13       Impact factor: 17.367

Review 7.  Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.

Authors:  Anna Csiszar; Stephanie Lehoux; Zoltan Ungvari
Journal:  Antioxid Redox Signal       Date:  2009-07       Impact factor: 8.401

Review 8.  Future perspectives for the treatment of pulmonary arterial hypertension.

Authors:  Hossein A Ghofrani; Robyn J Barst; Raymond L Benza; Hunter C Champion; Karen A Fagan; Friedrich Grimminger; Marc Humbert; Gérald Simonneau; Duncan J Stewart; Carlo Ventura; Lewis J Rubin
Journal:  J Am Coll Cardiol       Date:  2009-06-30       Impact factor: 24.094

9.  The genetics of pulmonary arterial hypertension in the post-BMPR2 era.

Authors:  Joshua P Fessel; James E Loyd; Eric D Austin
Journal:  Pulm Circ       Date:  2011 Jul-Sep       Impact factor: 3.017

10.  Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension.

Authors:  Henrick Horita; Seth B Furgeson; Allison Ostriker; Kyle A Olszewski; Timothy Sullivan; Leah R Villegas; Michelle Levine; Jane E Parr; Carlyne D Cool; Raphael A Nemenoff; Mary C M Weiser-Evans
Journal:  J Am Heart Assoc       Date:  2013-05-31       Impact factor: 5.501
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