Literature DB >> 11248669

The role of the Cdk5--p35 kinase in neuronal development.

G Paglini1, A Cáceres.   

Abstract

Cyclin-dependent kinase 5 (Cdk5) plays a key role in proper development of the nervous system. To be activated, Cdk5 associates with regulatory subunits not related to cyclins, such as p35 (the regulatory subunit of Cdk5). In this article, we review some of the experimental evidence supporting a central role for the Cdk5/p35 kinase in neuronal migration and process formation.

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Year:  2001        PMID: 11248669

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  20 in total

1.  The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic.

Authors:  G Paglini; L Peris; J Diez-Guerra; S Quiroga; A Cáceres
Journal:  EMBO Rep       Date:  2001-11-21       Impact factor: 8.807

Review 2.  Tau as a therapeutic target for Alzheimer's disease.

Authors:  A Boutajangout; E M Sigurdsson; P K Krishnamurthy
Journal:  Curr Alzheimer Res       Date:  2011-09       Impact factor: 3.498

3.  Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction.

Authors:  Yingchun Wang; Feng Yang; Yi Fu; Xiahe Huang; Wei Wang; Xinning Jiang; Marina A Gritsenko; Rui Zhao; Matthew E Monore; Olivier C Pertz; Samuel O Purvine; Daniel J Orton; Jon M Jacobs; David G Camp; Richard D Smith; Richard L Klemke
Journal:  J Biol Chem       Date:  2011-03-28       Impact factor: 5.157

Review 4.  Cdk5: mediator of neuronal development, death and the response to DNA damage.

Authors:  Jinqiu Zhu; Wenming Li; Zixu Mao
Journal:  Mech Ageing Dev       Date:  2011-05-11       Impact factor: 5.432

5.  Both cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes.

Authors:  Yoshinori Taniguchi; Jeffrey W Pippin; Henning Hagmann; Ronald D Krofft; Alice M Chang; Jiong Zhang; Yoshio Terada; Paul Brinkkoetter; Stuart J Shankland
Journal:  Am J Physiol Renal Physiol       Date:  2012-01-18

6.  Basolateral amygdala cdk5 activity mediates consolidation and reconsolidation of memories for cocaine cues.

Authors:  Fang-qiong Li; Yan-xue Xue; Ji-shi Wang; Qin Fang; Yan-qin Li; Wei-li Zhu; Ying-ying He; Jian-feng Liu; Li-fen Xue; Yavin Shaham; Lin Lu
Journal:  J Neurosci       Date:  2010-08-04       Impact factor: 6.167

7.  Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5.

Authors:  Huifang He; Kangwen Deng; Mustafa M Siddiq; Aung Pyie; Wilfredo Mellado; Sari S Hannila; Marie T Filbin
Journal:  J Neurosci       Date:  2016-03-09       Impact factor: 6.167

8.  Physiological and morphological characterization of dentate granule cells in the p35 knock-out mouse hippocampus: evidence for an epileptic circuit.

Authors:  Leena S Patel; H Jürgen Wenzel; Philip A Schwartzkroin
Journal:  J Neurosci       Date:  2004-10-13       Impact factor: 6.167

Review 9.  Selectivity and potency of cyclin-dependent kinase inhibitors.

Authors:  Jayalakshmi Sridhar; Nagaraju Akula; Nagarajan Pattabiraman
Journal:  AAPS J       Date:  2006-03-24       Impact factor: 4.009

10.  Oncogenes do not Fully Override Cell-intrinsic Traits: Pronounced Impact of the Cellular Programme.

Authors:  Józefa Węsierska-Gądek; Eva Walzi; Iva Dolečkova; Gerald Schmid
Journal:  Cancer Microenviron       Date:  2009-09-04
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