Literature DB >> 11240280

Mechanisms of cerebellar learning suggested by eyelid conditioning.

J F Medina1, W L Nores, T Ohyama, M D Mauk.   

Abstract

Classical eyelid conditioning has been used to great advantage in demonstrating that the cerebellum helps to improve movements through experience, and in identifying the underlying mechanisms. Results from recent studies support the hypotheses that learning occurs in both the cerebellar nucleus and cortex, and that these sites make different contributions. Specifically, results indicate that the cerebellar cortex is responsible for temporally specific learning. A combination of experimental and computational studies has been important for arriving at these conclusions, which seem to be applicable to the broad range of movements to which the cerebellum contributes.

Mesh:

Year:  2000        PMID: 11240280     DOI: 10.1016/s0959-4388(00)00154-9

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  83 in total

1.  Experience-dependent changes in cerebellar contributions to motor sequence learning.

Authors:  Julien Doyon; Allen W Song; Avi Karni; Francois Lalonde; Michelle M Adams; Leslie G Ungerleider
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-22       Impact factor: 11.205

2.  A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP.

Authors:  Varda Lev-Ram; Scott T Wong; Daniel R Storm; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-04       Impact factor: 11.205

3.  Reversing cerebellar long-term depression.

Authors:  Varda Lev-Ram; Samar B Mehta; David Kleinfeld; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-11       Impact factor: 11.205

Review 4.  The role of interpositus nucleus in eyelid conditioned responses.

Authors:  J M Delgado-García; A Gruart
Journal:  Cerebellum       Date:  2002-12       Impact factor: 3.847

5.  A recipe for bidirectional motor learning: using inhibition to cook plasticity in the vestibular nuclei.

Authors:  Javier F Medina
Journal:  Neuron       Date:  2010-11-18       Impact factor: 17.173

6.  Central cannabinoid receptors modulate acquisition of eyeblink conditioning.

Authors:  Adam B Steinmetz; John H Freeman
Journal:  Learn Mem       Date:  2010-10-28       Impact factor: 2.460

7.  Persistent changes in the intrinsic excitability of rat deep cerebellar nuclear neurones induced by EPSP or IPSP bursts.

Authors:  Wei Zhang; Jung Hoon Shin; David J Linden
Journal:  J Physiol       Date:  2004-10-21       Impact factor: 5.182

8.  Pattern-dependent, simultaneous plasticity differentially transforms the input-output relationship of a feedforward circuit.

Authors:  Spencer Lavere Smith; Thomas Stephen Otis
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

Review 9.  Nothing can be coincidence: synaptic inhibition and plasticity in the cerebellar nuclei.

Authors:  Jason R Pugh; Indira M Raman
Journal:  Trends Neurosci       Date:  2009-01-27       Impact factor: 13.837

10.  Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration.

Authors:  John J Crowley; Diasynou Fioravante; Wade G Regehr
Journal:  Neuron       Date:  2009-09-24       Impact factor: 17.173

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