Literature DB >> 11238237

Cytokine expression in the mouse brain in response to immune activation by Corynebacterium parvum.

W S Sheng1, S Hu, J M Ding, C C Chao, P K Peterson.   

Abstract

Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.

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Year:  2001        PMID： 11238237      PMCID： PMC96078          DOI： 10.1128/CDLI.8.2.446-448.2001

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  12 in total

Review 1.  Dynamic regulation of proinflammatory cytokines.

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Authors:  C C Chao; M DeLaHunt; S Hu; K Close; P K Peterson
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Authors:  W S Sheng; S Hu; A Lamkin; P K Peterson; C C Chao
Journal:  Clin Immunol Immunopathol       Date:  1996-11

Review 4.  Cytokines and sickness behavior.

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Review 10.  Molecular basis of sickness behavior.

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Journal:  Ann N Y Acad Sci       Date:  1998-09-29       Impact factor: 5.691
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