Literature DB >> 111873

A placebo-controlled trial of ketotifen (HC 20-511, Sandoz) in allergen induced asthma and comparison with disodium cromoglycate.

A Wells, B Taylor.   

Abstract

Ketotifen failed to protect against cat fur allergen induced asthma in a double blind placebo-controlled trial in ten asthmatic children. Disodium cromoglycate gave effective protection against the immediate and the late asthmatic reactions but there were no significant differences between the effects of ketotifen and a placebo.

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Year:  1979        PMID: 111873     DOI: 10.1111/j.1365-2222.1979.tb01548.x

Source DB:  PubMed          Journal:  Clin Allergy        ISSN: 0009-9090


  7 in total

Review 1.  Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders.

Authors:  S M Grant; K L Goa; A Fitton; E M Sorkin
Journal:  Drugs       Date:  1990-09       Impact factor: 9.546

2.  Drugs for asthma: mast-cell stabilisers.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-03-28

3.  Ketotifen in adult asthma.

Authors:  S G Spiro
Journal:  Br Med J       Date:  1980-03-22

4.  Effect of oral sodium cromoglycate and ketotifen in fish-induced bronchial asthma.

Authors:  R Ellul-Micallef
Journal:  Thorax       Date:  1983-07       Impact factor: 9.139

5.  The modification by ketotifen of respiratory responses to histamine and antigen in guinea-pigs.

Authors:  C Armour; D M Temple
Journal:  Agents Actions       Date:  1982-07

6.  A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma.

Authors:  C W Clarke; C S May
Journal:  Br J Clin Pharmacol       Date:  1980-11       Impact factor: 4.335

7.  Ketotifen in adult asthma.

Authors:  A J Dyson; A D Mackay
Journal:  Br Med J       Date:  1980-02-09
  7 in total

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