Literature DB >> 1118728

Inhibition of immune responses in vitro by specific antiserums to Ia antigens.

J A Frelinger, J E Niederhuber, D C Shreffler.   

Abstract

Mouse antiserums prepared against Ia antigens, which are products of I (immune response) region genes of the H-2 complex, can inhibit both primary (immunoglobulin M) and secondary (immunoglobulin G) immune responses in vitro by mouse spleen cultures to heterologous erythrocytes. Antiserums directed specifically at products of either the H-2K or H-2D loci have no effect on this response.

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Year:  1975        PMID： 1118728     DOI： 10.1126/science.1118728

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

1.  The major histocompatibility complex--comparison in the mouse, man, and the rat. A review.

Authors:  T J Gill; D V Cramer; H W Kunz
Journal:  Am J Pathol       Date:  1978-03       Impact factor: 4.307

2.  Inhibition of proliferative and plaque-forming cell responses by human bone-marrow-derived lymphocytes from peripheral blood by antisera to the p23, 30 antigen.

Authors:  S M Friedman; J M Breard; R E Humphreys; J L Strominger; S F Schlossman; L Chess
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

3.  Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex.

Authors:  J Silver; W A Russell; B L Reis; J A Frelinger
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

4.  Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes.

Authors:  G A Bishop; M S McMillan; G Haughton; J A Frelinger
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

5.  Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha.

Authors:  M M Davis; D I Cohen; E A Nielsen; M Steinmetz; W E Paul; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

6.  Evidence for two populations of B-L (Ia-like) molecules encoded by the chicken MHC.

Authors:  M Crone; J Jensenius; C Koch
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

7.  Variable synthesis and expression of E alpha and Ae (E beta) Ia polypeptide chains in mice of different H-2 haplotypes.

Authors:  P P Jones; D B Murphy; H O McDevitt
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

8.  Inhibition of antigen-induced proliferation of T cells from radiation-induced bone marrow chimeras by a monoclonal antibody directed against an Ia determinant on the antigen-presenting cell.

Authors:  D L Longo; R H Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

9.  Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.

Authors:  M Pierres; R N Germain; M E Dorf; B Benacerraf
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

10.  Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to Ia determinants.

Authors:  D Faustman; V Hauptfeld; P Lacy; J Davie
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205
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