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Literature DB >> 111762

Anti-keratin antibodies in rheumatoid arthritis.

B J Young, R K Mallya, R D Leslie, C J Clark, T J Hamblin.

Abstract

A naturally occurring antibody that reacts with the keratinised tissue of animal oesophagus was found in the serum of 75 out of 129 patients (58%) with classical or definite rheumatoid arthritis (RA) but not in sera from 105 healthy people. Detection of the antibody, which is unrelated to rheumatoid factor, is more specific for RA than the reaction in the sheep-cell agglutination test but less sensitive.

Entities: Disease Species

Mesh：

Substances：

Year: 1979 PMID： 111762 PMCID： PMC1596039 DOI： 10.1136/bmj.2.6182.97

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

8 in total

1. Clinical significance of the rheumatoid serum factor.

Authors: J H KELLGREN; J BALL
Journal: Br Med J Date: 1959-02-28

Review 2. The structure and chemistry of keratin fibers.

Authors: J H Bradbury
Journal: Adv Protein Chem Date: 1973

3. Studies on isolated keratin fractions from mammalian epidermis. II. Immunological and immuno-electrophoretic comparison of the fractions.

Authors: F W Bauer
Journal: Dermatologica Date: 1972

4. Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors: G Mancini; A O Carbonara; J F Heremans
Journal: Immunochemistry Date: 1965-09

5. Immunological studies on wool proteins.

Authors: R Frater
Journal: Aust J Biol Sci Date: 1968-08

6. Isolation of the polypeptide chains of prekeratin.

Authors: L D Lee; B C Fleming; R F Waitkus; H P Baden
Journal: Biochim Biophys Acta Date: 1975-11-18

7. Immunological and immuno-fluorescent studies on keratin of the hair follicle.

Authors: D J Kemp; G E Rogers
Journal: J Cell Sci Date: 1970-07 Impact factor: 5.285

8. Interaction of aggregated -globulin with B lymphocytes.

Authors: H B Dickler; H G Kunkel
Journal: J Exp Med Date: 1972-07-01 Impact factor: 14.307

8 in total

101 in total

1. Unlocking the "PAD" lock on rheumatoid arthritis.

Authors: P J Utz; M C Genovese; W H Robinson
Journal: Ann Rheum Dis Date: 2004-04 Impact factor: 19.103

2. Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.

Authors: Altan Ercan; Jing Cui; Dereck E W Chatterton; Kevin D Deane; Melissa M Hazen; William Brintnell; Colin I O'Donnell; Lezlie A Derber; Michael E Weinblatt; Nancy A Shadick; David A Bell; Ewa Cairns; Daniel H Solomon; V Michael Holers; Pauline M Rudd; David M Lee
Journal: Arthritis Rheum Date: 2010-08

3. Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis.

Authors: David C Wilson; Anthony D Marinov; Harry C Blair; Daniel S Bushnell; Susan D Thompson; Yury Chaly; Raphael Hirsch
Journal: Arthritis Rheum Date: 2010-08

Anti-keratin antibodies in rheumatoid arthritis.

1. Clinical significance of the rheumatoid serum factor.

Review 2. The structure and chemistry of keratin fibers.

3. Studies on isolated keratin fractions from mammalian epidermis. II. Immunological and immuno-electrophoretic comparison of the fractions.

4. Immunochemical quantitation of antigens by single radial immunodiffusion.

5. Immunological studies on wool proteins.

6. Isolation of the polypeptide chains of prekeratin.

7. Immunological and immuno-fluorescent studies on keratin of the hair follicle.

8. Interaction of aggregated -globulin with B lymphocytes.

1. Unlocking the "PAD" lock on rheumatoid arthritis.

2. Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.

3. Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis.

4. New markers and an old phenomenon: prozone effect disturbing detection of filaggrin (keratin) autoantibodies.

5. Anti-CCP antibodies have more diagnostic impact than rheumatoid factor (RF) in a population tested for RF.

6. Antikeratin antibody in rheumatoid and psoriatic arthritis.

Review 7. Anti-citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis.

Review 8. Anti-citrullinated peptide antibodies and their value for predicting responses to biologic agents: a review.

9. Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.

10. Association of anti-CCP positivity with serum ferritin and DAS-28.