| Literature DB >> 11173115 |
P D Keightley1, A Eyre-Walker.
Abstract
The 'mutational deterministic' hypothesis proposes that a high genomic rate of deleterious mutation (U) might maintain sexual reproduction. Our recent work casts doubt on this, as we estimate a low U for sexually reproducing species with short generation times. Following criticism by Kondrashov, here we defend our methods for estimating U and challenge the mutational deterministic hypothesis.Mesh：
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Year: 2001 PMID： 11173115 DOI： 10.1016/s0168-9525(00)02177-6
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639