Literature DB >> 11170674

Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae.

M Kuroda1, Y Mimaki, A Yokosuka, Y Sashida, J A Beutler.   

Abstract

Further phytochemical analysis of the bulbs of Ornithogalum saundersiae has yielded two new cytotoxic cholestane triglycosides (1 and 2). The structures of these compounds were determined by spectroscopic analysis, including 2D NMR spectroscopic data, and the results of hydrolytic cleavage. Compounds 1 and 2 and several analogues were evaluated for their cytotoxicity against HL-60 cells.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11170674     DOI: 10.1021/np0003084

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Synthesis of biotinylated OSW-1.

Authors:  Ying Kang; Changgang Lou; Kausar Begam Riaz Ahmed; Peng Huang; Zhendong Jin
Journal:  Bioorg Med Chem Lett       Date:  2009-07-14       Impact factor: 2.823

2.  Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals.

Authors:  Stephen Lockett; Chrissie Verma; Alla Brafman; Prabhakar Gudla; Kaustav Nandy; Yoshihiro Mimaki; Philip L Fuchs; Joseph Jaja; Karlyne M Reilly; John Beutler; Thomas J Turbyville
Journal:  Cytometry A       Date:  2014-02-11       Impact factor: 4.355

3.  Structural Characterization of Cholestane Rhamnosides from Ornithogalum saundersiae Bulbs and Their Cytotoxic Activity against Cultured Tumor Cells.

Authors:  Tomoki Iguchi; Minpei Kuroda; Rei Naito; Tomoyuki Watanabe; Yukiko Matsuo; Akihito Yokosuka; Yoshihiro Mimaki
Journal:  Molecules       Date:  2017-07-25       Impact factor: 4.411

4.  The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity.

Authors:  Ming Liu; Jian-Qiang Kong
Journal:  Acta Pharm Sin B       Date:  2018-05-01       Impact factor: 11.413

5.  OSW-1 inhibits tumor growth and metastasis by NFATc2 on triple-negative breast cancer.

Authors:  Xiaorong Ding; Yumei Li; Jun Li; Yongmei Yin
Journal:  Cancer Med       Date:  2020-06-08       Impact factor: 4.452

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.